Human cytomegalovirus entry into cells.
作者信息
Vanarsdall Adam L, Johnson David C
机构信息
Oregon Health & Sciences University, Portland, OR 97239, United States.
出版信息
Curr Opin Virol. 2012 Feb;2(1):37-42. doi: 10.1016/j.coviro.2012.01.001. Epub 2012 Jan 30.
Abstract
摘要
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Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells.人巨细胞病毒糖蛋白 gO 与 gH/gL 复合物，促进干扰病毒进入人成纤维细胞，但不进入上皮细胞。
J Virol. 2011 Nov;85(22):11638-45. doi: 10.1128/JVI.05659-11. Epub 2011 Aug 31.
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Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture.牛痘细胞外病毒通过巨胞饮作用和酸激活的膜破裂进入细胞。
EMBO J. 2011 Jul 26;30(17):3647-61. doi: 10.1038/emboj.2011.245.
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Capturing the herpes simplex virus core fusion complex (gB-gH/gL) in an acidic environment.在酸性环境下捕获单纯疱疹病毒核心融合复合物（gB-gH/gL）。
J Virol. 2011 Jul;85(13):6175-84. doi: 10.1128/JVI.00119-11. Epub 2011 Apr 20.
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Fusing structure and function: a structural view of the herpesvirus entry machinery.融合结构与功能：疱疹病毒进入机制的结构观
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Protein pUL128 of human cytomegalovirus is necessary for monocyte infection and blocking of migration.人巨细胞病毒的蛋白 pUL128 对于单核细胞感染和迁移阻断是必需的。
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Rhesus and human cytomegalovirus glycoprotein L are required for infection and cell-to-cell spread of virus but cannot complement each other.恒河猴和人巨细胞病毒糖蛋白 L 是病毒感染和细胞间传播所必需的，但不能相互补充。
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Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22641-6. doi: 10.1073/pnas.1011806108. Epub 2010 Dec 13.
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Cascade of events governing cell-cell fusion induced by herpes simplex virus glycoproteins gD, gH/gL, and gB.疱疹病毒糖蛋白 gD、gH/gL 和 gB 诱导的细胞融合的级联事件。
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Herpes simplex virus glycoprotein D interferes with binding of herpesvirus entry mediator to its ligands through downregulation and direct competition.单纯疱疹病毒糖蛋白 D 通过下调和直接竞争干扰疱疹病毒进入介体与其配体的结合。
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