Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
Department of Microbiology, Old Medical School, Leeds General Infirmary, Leeds LS1 3EX, UK.
J Med Microbiol. 2012 Jun;61(Pt 6):755-761. doi: 10.1099/jmm.0.039693-0. Epub 2012 Mar 22.
Granulicatella species, along with the genus Abiotrophia, were originally known as 'nutritionally variant streptococci'. They are a normal component of the oral flora, but have been associated with a variety of invasive infections in man and are most noted as a cause of bacterial endocarditis. It is often advised that Granulicatella endocarditis should be treated in the same way as enterococcal endocarditis. We review here the published data concerning diagnosis and treatment of Granulicatella infection, and include some observations from local cases, including four cases of endocarditis.
颗粒菌属与拟杆菌属原本被称为“营养变异链球菌”。它们是口腔菌群的正常组成部分，但已与多种侵袭性人类感染有关，最著名的是细菌性心内膜炎的病因。通常建议采用与肠球菌心内膜炎相同的方法治疗颗粒菌心内膜炎。我们在此回顾了有关颗粒菌感染的诊断和治疗的已发表数据，并包括了来自本地病例的一些观察结果，包括四例心内膜炎。
