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Iatrogenic Cushing syndrome after epidural steroid injections for lumbar radiculopathy in an HIV-infected patient treated with ritonavir: a case report highlighting drug interactions for spine interventionalists.

作者信息

Grierson Matthew J, Harrast Mark A

机构信息

Department of Rehabilitation Medicine, Box 356490, BB-928 Health Sciences Bldg, University of Washington, Seattle, WA 98195-6490, USA.

出版信息

PM R. 2012 Mar;4(3):234-7. doi: 10.1016/j.pmrj.2011.10.003.

DOI:10.1016/j.pmrj.2011.10.003
PMID:22443962
Abstract
摘要

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Iatrogenic Cushing's syndrome and secondary adrenal insufficiency after a single intra-articular administration of triamcinolone acetonide in HIV-infected patients treated with ritonavir.在接受利托那韦治疗的HIV感染患者中，单次关节腔内注射曲安奈德后发生医源性库欣综合征和继发性肾上腺功能不全。
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Iatrogenic Cushing's syndrome in an HIV-infected patient treated with inhaled corticosteroids (fluticasone propionate) and low dose ritonavir enhanced PI containing regimen.一名感染人类免疫缺陷病毒（HIV）的患者因吸入皮质类固醇（丙酸氟替卡松）和含低剂量利托那韦的增强型蛋白酶抑制剂（PI）方案治疗而发生医源性库欣综合征。
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引用本文的文献

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2
Iatrogenic adrenal suppression following caudal epidural and facet joint injection.骶管硬膜外腔和小关节注射后的医源性肾上腺抑制
BMJ Case Rep. 2019 Feb 21;12(2):e225828. doi: 10.1136/bcr-2018-225828.
3
Safety of Epidural Corticosteroid Injections.硬膜外皮质类固醇注射的安全性。
Drugs R D. 2016 Mar;16(1):19-34. doi: 10.1007/s40268-015-0119-3.
4
Iatrogenic cushing syndrome secondary to ritonavir-epidural triamcinolone interaction: an illustrative case and review.由利托那韦与硬膜外注射曲安奈德相互作用引起的医源性库欣综合征：病例分析及文献综述
Interdiscip Perspect Infect Dis. 2014;2014:849432. doi: 10.1155/2014/849432. Epub 2014 May 7.
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Triamcinolone and ritonavir leading to drug-induced Cushing syndrome and adrenal suppression: description of a new case and review of the literature.曲安奈德和利托那韦导致药物性库欣综合征及肾上腺抑制：1例新病例报道及文献复习
Infection. 2013 Dec;41(6):1183-7. doi: 10.1007/s15010-013-0506-z. Epub 2013 Jul 20.