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在一名接受克力芝治疗HIV-1的患者中,眼眶底注射曲安奈德导致库欣综合征。

Orbital floor triamcinolone causing Cushing's syndrome in a patient treated with Kaletra for HIV 1.

作者信息

McConkey Hannah Zelie Ruth, Williams Helen, Kulasegaram Ranjababu, Graham Elizabeth

机构信息

Medical Eye Unit, GSTT, London, UK.

出版信息

BMJ Case Rep. 2013 Feb 25;2013:bcr0220125849. doi: 10.1136/bcr.02.2012.5849.

DOI:10.1136/bcr.02.2012.5849
PMID:23440982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3597379/
Abstract

We report the first known case of iatrogenic cushingoid features following orbital floor triamcinolone, a synthetic corticosteroid, in a patient taking Kaletra (200 mg lopinavir/50 mg ritonavir) twice daily and Truvada (tenofovir/emtricitabine) once daily for HIV 1. Previous reports have included similar findings following epidural triamcinolone injections and with inhaled fluticasone.

摘要

我们报告了首例在一名每天服用两次克力芝(200毫克洛匹那韦/50毫克利托那韦)和每天服用一次特鲁瓦达(替诺福韦/恩曲他滨)治疗HIV 1的患者中,眼眶底注射合成皮质类固醇曲安奈德后出现医源性库欣样特征的已知病例。既往报告包括硬膜外注射曲安奈德和吸入氟替卡松后出现的类似发现。

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Orbital floor triamcinolone causing Cushing's syndrome in a patient treated with Kaletra for HIV 1.在一名接受克力芝治疗HIV-1的患者中,眼眶底注射曲安奈德导致库欣综合征。
BMJ Case Rep. 2013 Feb 25;2013:bcr0220125849. doi: 10.1136/bcr.02.2012.5849.
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本文引用的文献

1
Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir.一名接受利托那韦-洛匹那韦治疗的1型艾滋病毒感染患者在硬膜外注射曲安奈德后发生医源性库欣综合征。
Clin Infect Dis. 2008 Dec 15;47(12):e97-9. doi: 10.1086/593314.