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足部结核:溶骨性类型。

Tuberculosis of the foot: An osteolytic variety.

作者信息

Dhillon Mandeep S, Aggarwal Sameer, Prabhakar Sharad, Bachhal Vikas

机构信息

Department of Orthopedics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Orthop. 2012 Mar;46(2):206-11. doi: 10.4103/0019-5413.93683.

Abstract

BACKGROUND

Foot involvement in osteoarticular tuberculosis is uncommon and isolated bony involvement of foot bones with an osteolytic defect is even more rare; diagnostic and therapeutic delays can occur, worsening the prognosis. We present a retrospective series of osteolytic variety of foot tuberculosis.

MATERIALS AND METHODS

We present 24 osteolytic variety of foot tuberculosis (Eleven calcaneus, four cuboid, two cunieforms, one talus, three metatarsals, three phalanges) out of 92 foot TB cases collected over last 20 years. There were 16 adults and eight children. Tissue diagnosis was established in 23 of 24 cases based on PCR AFB staining, culture, and histopathology. Surgical intervention was reserved for patients with either a juxtaarticular focus threatening to involve a joint or an impending collapse of a midfoot bone with cystic destruction.

RESULTS

Fifteen cases had an osteolytic lesion on the radiographs resembling a space-occupying lesion, five had patchy osteolysis, while four showed coke like sequestra; one patient had a lesion in two bones. Antitubercular chemotherapy after biopsy was sufficient to heal the lesion in 19 cases, while in five cases surgical debridement needed to be done. The lesions healed eventually. At an average followup of 8.3 years, (range 2-15 years) there were no recurrences and all patients were free from pain, with no restriction of movements. Six patients complained of occasional pain during walking on uneven ground.

CONCLUSION

When tuberculous pathology is limited to the bone, the prognosis is better than in articular disease, as there is less deformity, and hence, less residual pain and disability.

摘要

背景

足部骨关节结核较少见,而足部骨骼单纯出现溶骨性缺损的情况更为罕见;诊断和治疗的延误可能发生,从而使预后恶化。我们报告一组足部结核溶骨型的回顾性病例。

材料与方法

在过去20年收集的92例足部结核病例中,我们报告了24例足部结核溶骨型病例(11例跟骨、4例骰骨、2例楔骨、1例距骨、3例跖骨、3例趾骨)。其中16例为成人,8例为儿童。24例中有23例通过聚合酶链反应抗酸杆菌染色、培养和组织病理学检查确立了组织学诊断。对于病灶位于关节旁有累及关节风险或中足骨因囊性破坏即将塌陷的患者,才进行手术干预。

结果

15例患者的X线片显示溶骨性病变类似占位性病变,5例为斑片状骨质溶解,4例显示有煤渣样死骨;1例患者两块骨骼均有病变。活检后进行抗结核化疗,19例患者的病灶得以愈合,5例患者需要进行手术清创。最终病灶均愈合。平均随访8.3年(范围2 - 15年),无复发,所有患者均无疼痛,活动不受限。6例患者在不平地面行走时偶尔感到疼痛。

结论

当结核病变局限于骨骼时,预后优于关节疾病,因为畸形较少,因此残留疼痛和残疾也较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d267/3308663/db6ebd092c03/IJOrtho-46-206-g003.jpg

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