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超越“g”:测试非痴呆人群痴呆过程的新模式。

Getting Past "g": testing a new model of dementing processes in persons without dementia.

机构信息

Department of Psychiatry, the University of Texas Health Science Center, San Antonio, TX, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):37-46. doi: 10.1176/appi.neuropsych.11040078.

Abstract

The cognitive correlates of functional status are essential to dementia case-finding. The authors have used structural-equation models to explicitly distinguish dementia-relevant variance in cognitive task performance (i.e., δ) from the variance that is unrelated to a dementing process (i.e., g'). Together, g' and δ comprise Spearman's "g." Although δ represents only a small fraction of the total variance in cognitive task performance, it is more strongly associated with dementia severity than is g'. In this analysis, the authors test whether δ can predict future cognitive decline in persons clinically without dementia at baseline. These results have implications for the clinical assessment of dementia and suggest that functional status should assume a more important role.

摘要

认知功能与功能状态密切相关,是痴呆病例发现的关键。作者采用结构方程模型,明确区分了认知任务表现中与痴呆相关的差异(即 δ)和与痴呆过程无关的差异(即 g')。g'和 δ共同构成了斯皮尔曼的“g”。尽管 δ仅占认知任务表现总方差的一小部分,但它与痴呆严重程度的相关性强于 g'。在本分析中,作者检验了 δ 是否可以预测基线时临床无痴呆的个体未来认知能力下降。这些结果对痴呆的临床评估具有重要意义,并表明功能状态应发挥更重要的作用。

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