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功能状态的认知关联:美国神经精神协会研究委员会的综述

The cognitive correlates of functional status: a review from the Committee on Research of the American Neuropsychiatric Association.

作者信息

Royall Donald R, Lauterbach Edward C, Kaufer Daniel, Malloy Paul, Coburn Kerry L, Black Kevin J

机构信息

Department of Psychiatry, UTHSCSA, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 2007 Summer;19(3):249-65. doi: 10.1176/jnp.2007.19.3.249.

Abstract

This report reviews the state of the literature and opportunities for research related to the cognitive correlates of functional status. The prediction of functional capacity on the basis of cognitive test performance is an important aspect of neuropsychological assessment. Moreover, functional impairment or "disability" is an essential part of dementia case finding. Nevertheless, relatively little attention has been given to the empirical study of the specific cognitive correlates of functional outcomes. What literature is available suggests that 1) the variance in functional status that can be specifically attributed to cognition is surprisingly modest; 2) some cognitive domains may be more relevant to functional capacity than others; 3) some measures of executive control function are relatively strong correlates of functional capacities, particularly medical or financial decision-making; and 4) "general" cognitive screening tests are surprisingly strong correlates of functional status. These findings are of particular significance to dementia case finding, epidemiology, and treatment. The extensive literature on functional status has yet to be integrated with the equally extensive literature on cognitive assessment. Better integration of cognitive and functional assessments would offer greater clinical utility. However, psychometric batteries may have to be redesigned to maximize their capacity to capture the variance in functional outcomes.

摘要

本报告回顾了与功能状态的认知关联相关的文献现状及研究机会。基于认知测试表现预测功能能力是神经心理学评估的一个重要方面。此外,功能损害或“残疾”是痴呆症病例发现的重要组成部分。然而,相对较少的关注集中在功能结果的特定认知关联的实证研究上。现有文献表明:1)可明确归因于认知的功能状态差异出人意料地小;2)某些认知领域可能比其他领域与功能能力更相关;3)一些执行控制功能的测量与功能能力,特别是医疗或财务决策,有较强的相关性;4)“一般”认知筛查测试与功能状态有惊人的强相关性。这些发现对痴呆症病例发现、流行病学和治疗具有特别重要的意义。关于功能状态的大量文献尚未与同样大量的认知评估文献整合。更好地整合认知和功能评估将提供更大的临床效用。然而,可能必须重新设计心理测量量表,以最大限度地提高其捕捉功能结果差异的能力。

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