BM, Research Centre of Applied & Preventive Cardiovascular Medicine, Turku, Finland.
Circulation. 2012 Apr 24;125(16):1971-8. doi: 10.1161/CIRCULATIONAHA.111.073585. Epub 2012 Mar 27.
The American Heart Association (AHA) defined a new concept, cardiovascular health, and determined metrics needed to monitor it over time as part of its 2020 Impact Goal definition. Ideal cardiovascular health is defined by the presence of both ideal health behaviors and ideal health factors. The applicability of this concept to a cohort of children and its relationship with cardiometabolic outcomes in adulthood has not been reported.
The sample comprised 856 participants aged 12 to 18 years (mean age 15.0 years) from the Cardiovascular Risk in Young Finns Study cohort. Participants were followed up for 21 years since baseline (1986) and had data available concerning health factors and behaviors in childhood and cardiometabolic outcomes in adulthood (2007). The number of ideal cardiovascular health metrics present in childhood was associated with reduced risk of hypertension (odds ratio [95% confidence interval] 0.66 [0.52-0.85], P<0.001), metabolic syndrome (0.66 [0.52-0.77], P<0.001), high low-density lipoprotein cholesterol (0.66 [0.52-0.85], P=0.001), and high-risk carotid artery intima-media thickness (0.75 [0.60-0.94], P=0.01) in adulthood. All analyses were age and sex adjusted, and the results were not altered after additional adjustment with socioeconomic status.
The number of ideal cardiovascular health metrics present in childhood predicts subsequent cardiometabolic health in adulthood. Our findings suggest that pursuit of ideal cardiovascular health in childhood is important to prevent cardiometabolic outcomes in adulthood.
美国心脏协会（AHA）定义了一个新概念，即心血管健康，并确定了随着时间的推移监测它所需的指标，作为其 2020 年影响目标定义的一部分。理想的心血管健康由理想的健康行为和理想的健康因素共同定义。这一概念在儿童队列中的适用性及其与成年后代谢心血管结局的关系尚未得到报道。
该样本由来自心血管风险在年轻芬兰人中的研究队列的 856 名年龄在 12 至 18 岁（平均年龄 15.0 岁）的参与者组成。参与者从基线（1986 年）开始被随访 21 年，并且在儿童时期有健康因素和行为以及成年期代谢心血管结局的数据。儿童时期存在的理想心血管健康指标数量与降低高血压风险相关（优势比[95%置信区间]0.66[0.52-0.85]，P<0.001）、代谢综合征（0.66[0.52-0.77]，P<0.001）、高低密度脂蛋白胆固醇（0.66[0.52-0.85]，P=0.001）和高风险颈动脉内膜中层厚度（0.75[0.60-0.94]，P=0.01）。所有分析均进行了年龄和性别调整，并且在进一步根据社会经济地位进行调整后，结果并未改变。
儿童时期存在的理想心血管健康指标数量预测成年后随后的代谢心血管健康。我们的发现表明，在儿童时期追求理想的心血管健康对于预防成年后的代谢心血管结局很重要。
