Department of Medical and Surgical Sciences, University of Padua, Via Ospedale n.105, Padua, Italy.
J Endocrinol Invest. 2012 Apr;35(4):419-24. doi: 10.3275/8302. Epub 2012 Mar 22.
Selenium (Se) is an important element that exerts its effects on the selenoproteins. It is an essential component of the glutathione peroxidase enzymes, which have anti-oxidant and anti-inflammatory properties, and a component of iodothyronine selenodeiodinases, which catalyze the extrathyroid production of T3 from T4. Se is important to several aspects of thyroid homeostasis and may influence the natural course of thyroid diseases such as autoimmune thyroiditis (AIT). This review analyzes the effects of Se supplementation in patients with AIT, based on the studies published on this issue to date.
硒（Se）是一种重要的元素，对硒蛋白发挥作用。它是谷胱甘肽过氧化物酶的重要组成部分，具有抗氧化和抗炎特性，也是甲状腺素硒代碘酶的组成部分，可催化 T4 向 T3 的甲状腺外生成。硒对甲状腺稳态的几个方面都很重要，并且可能影响自身免疫性甲状腺炎（AIT）等甲状腺疾病的自然病程。本综述根据迄今为止关于该问题发表的研究，分析了 AIT 患者补充硒的效果。
