Department of Urology, Erasmus MC, Rotterdam, The Netherlands.
Curr Opin Urol. 2012 May;22(3):216-21. doi: 10.1097/MOU.0b013e328351dcc7.
To inform readers on the ongoing activities of the Prostate cancer Research International: Active Surveillance (PRIAS) study in the light of current findings and research problems on active surveillance worldwide.
Recent data from the PRIAS study combined with PubMed-based literature from the last 3 years.
The PRIAS study is a rapidly growing registry for active surveillance of low-risk prostate cancer. The study is conducted worldwide, facilitated by an electronic Web-based decision tool with password-restricted access for physicians. Inclusion and monitoring is performed according to protocol. Over 2000 men have been included from over 100 participating centres in 17 countries in four continents. The study was initiated in December 2006. Risk reclassification on repeat biopsy during follow-up has occurred in 27% of biopsied men, although a switch towards active therapy has been performed in 22% of the total cohort.
根据目前全球主动监测研究中关于主动监测的现有发现和研究问题，向读者介绍前列腺癌研究国际：主动监测（PRIAS）研究的最新进展。
来自 PRIAS 研究的最新数据以及过去 3 年基于 PubMed 的文献。
PRIAS 研究是一个快速发展的主动监测低危前列腺癌的登记处。该研究在全球范围内开展，通过一个电子网络决策工具进行，该工具对医生进行密码限制访问。根据协议进行纳入和监测。来自四大洲 17 个国家的 100 多个参与中心的 2000 多名男性参与了该研究。该研究于 2006 年 12 月启动。在随访期间重复活检时出现了 27%的男性风险重新分类，尽管在总队列中，有 22%的男性转向了主动治疗。
