Ahmed Stephanie, McNanley Anna, Perevich Maryann, Glantz John Christopher, Buchsbaum Gunhilde
From the University of Rochester Medical Center, Rochester, NY.
Female Pelvic Med Reconstr Surg. 2010 Nov;16(6):327-30. doi: 10.1097/SPV.0b013e3181ee66ad.
: There is not currently a standard definition of "normal" for uroflowmetry parameters, particularly with respect to spontaneous voids or multiple repeated measurements within an individual. Our study aimed to describe uroflow parameters for "normal" in a group of healthy women based on repeated measurements.
: Spontaneous voids of twelve healthy women were recorded over two weeks. Additionally, one prompted void per subject was recorded. Prompted voids were compared to the subjects' spontaneous voids. These voids were also compared to those of patients evaluated for urinary incontinence. Groups were compared using paired t tests.
: The mean voided volume was 306 ml and the mean maximum flow rate was 49 ml/s. The prompted voids were lower in volume, maximum flow, and duration than spontaneous voids. When corrected for volume, these differences were not significant. Maximum flow rates in patients evaluated for urinary incontinence were lower than those of volunteers.
: Uroflowmetry parameters vary widely between and within healthy volunteers. Prompted voids are representative of spontaneous voids. Maximum flow rates of patients evaluated for urinary incontinence were lower than those of volunteers. In a group of healthy volunteers voiding in a private, spontaneous setting, a maximum flow rate of lower than 17 ml/s (2 SDs below the mean) might be considered abnormally low.
目前尿流率参数尚无“正常”的标准定义，尤其是对于自然排尿或个体内多次重复测量而言。我们的研究旨在基于重复测量描述一组健康女性“正常”的尿流参数。
记录12名健康女性在两周内的自然排尿情况。此外，还记录了每位受试者一次诱导排尿情况。将诱导排尿与受试者的自然排尿进行比较。这些排尿情况还与因尿失禁接受评估的患者的排尿情况进行比较。采用配对t检验对各组进行比较。
平均排尿量为306毫升，平均最大尿流率为49毫升/秒。诱导排尿的尿量、最大尿流率和持续时间均低于自然排尿。经尿量校正后，这些差异不显著。因尿失禁接受评估的患者的最大尿流率低于志愿者。
健康志愿者之间以及个体内部的尿流率参数差异很大。诱导排尿可代表自然排尿。因尿失禁接受评估的患者的最大尿流率低于志愿者。在一组在私密、自然环境中排尿的健康志愿者中，最大尿流率低于17毫升/秒（比平均值低2个标准差）可能被认为异常低。
