Komesu Yuko M, Schrader Ronald M, Rogers Rebecca G, Ketai Loren H
From the *Department of Obstetrics & Gynecology, Health Sciences Center, †Department of Biostatistics, Clinical and Translational Science Center, Health Sciences Center, and ‡Department of Radiology, Health Sciences Center, University of New Mexico, Albuquerque, NM.
Female Pelvic Med Reconstr Surg. 2011 Jan;17(1):17-23. doi: 10.1097/SPV.0b013e31820446e6.
: To estimate 2-year incidence, remission, and predictors of urgency urinary incontinence (UUI) in a community-based population of women 50 years or older.
: We analyzed the 2004 to 2006 data in the Health and Retirement Study. Subjects were women 50 years or older with baseline and follow-up UUI information. Urgency urinary incontinence incidence and remission were calculated. Predictors of UUI progression and improvement were estimated controlling for age, ethnicity, body mass index, parity, psychiatric illness, medical comorbidities, functional limitations, and stress urinary incontinence. We evaluated whether baseline UUI status predicted follow-up status and used multivariable logistic regression to identify predictor variables.
: A total of 8581 women reported UUI status at baseline and follow-up. Of 7244 women continent at baseline, 268 affirmed UUI at follow-up for a 2-year incidence of 3.7%. Of 581 women with UUI at baseline, 150 were continent at follow-up for a 2-year remission of 25.8%. Predictors of UUI development included increased age (7th and 10th decades compared with 6th decade; OR, 1.5 and 7.2; confidence interval [CI], 1.1-2.1 and 4.2-12.5, respectively), obesity (OR, 1.6; CI, 1.2-2.1), history of psychiatric illness (OR, 1.6; CI, 1.3-2.0), functional limitations (OR, 6.2; CI, 4.2-9.2), and stress urinary incontinence (OR, 5.0; CI, 3.0-8.3). Women who denied UUI at baseline were also likely to deny UUI at follow-up (OR, 47.4; CI, 22.9-98.1).
: In this community-based population of women 50 years or older, UUI incidence was low and remission was high. Predictors of UUI included increased age, severe obesity, functional limitations, a positive psychiatric history, and incontinence status at baseline.
评估50岁及以上社区女性中急迫性尿失禁（UUI）的2年发病率、缓解率及预测因素。
我们分析了健康与退休研究中2004年至2006年的数据。研究对象为50岁及以上且有基线和随访UUI信息的女性。计算急迫性尿失禁的发病率和缓解率。在控制年龄、种族、体重指数、产次、精神疾病、内科合并症、功能受限及压力性尿失禁的情况下，评估UUI进展和改善的预测因素。我们评估了基线UUI状态是否能预测随访状态，并使用多变量逻辑回归来确定预测变量。
共有8581名女性报告了基线和随访时的UUI状态。在基线时尿控正常的7244名女性中，268名在随访时被确诊为UUI，2年发病率为3.7%。在基线时有UUI的581名女性中，150名在随访时尿控正常，2年缓解率为25.8%。UUI发生的预测因素包括年龄增加（与60岁相比，70岁和80岁；比值比[OR]分别为1.5和7.2；置信区间[CI]分别为1.1 - 2.1和4.2 - 12.5）、肥胖（OR，1.6；CI，1.2 - 2.1）、精神疾病史（OR，1.6；CI，1.3 - 2.0）、功能受限（OR，6.2；CI，4.2 - 9.2）以及压力性尿失禁（OR，5.0；CI，3.0 - 8.3）。在基线时否认有UUI的女性在随访时也很可能否认有UUI（OR, 47.4；CI，22.9 - 98.1）。
在这个50岁及以上的社区女性人群中，UUI发病率低且缓解率高。UUI的预测因素包括年龄增加、重度肥胖、功能受限、阳性精神病史以及基线时的失禁状态。
