Service de Réanimation Médicale - Hôpital Ambroise-Paré, Boulogne (Paris-West), France.
Expert Rev Respir Med. 2012 Apr;6(2):155-62. doi: 10.1586/ers.12.13.
The FALLS-protocol is included in a limited investigation to diagnose the cause of shock. After simple echocardiography has ruled out obstructive shock (tamponade, pulmonary embolism), the lung is investigated. Absence of disseminated lung rockets rules out cardiogenic shock. At this point, hypovolemic and septic shock are differential diagnoses (rarities apart), and the FALLS-protocol provides fluid therapy with constant monitoring of lung artifacts. Hypovolemic shock will eventually improve - septic shock will not, and the slight excess fluid creates an early, silent stage of interstitial edema, demonstrated by B-lines, demanding interruption of fluid therapy. This sequential approach, combined with the usual, clinical, biochemical and echocardiographic parameters, must be evaluated in multicenter studies.
FALLS 方案被纳入一项旨在明确休克病因的有限度调查中。在经过简单的超声心动图排除梗阻性休克(心包填塞、肺栓塞)后,进一步探查肺部。如果不存在弥漫性肺实变征,则可排除心源性休克。此时,需鉴别诊断低血容量性和脓毒性休克(两者均为少见病因),FALLS 方案可提供液体治疗,并持续监测肺部伪影。低血容量性休克最终会改善,而脓毒性休克则不会,且少量多余的液体可导致亚临床的间质性水肿早期阶段,B 线可对此作出提示,此时需要中断液体治疗。这种序贯方法,结合临床、生化和超声心动图的常用参数,必须在多中心研究中进行评估。