Intensive Care Unit, Derby Street, Nepean, Penrith, Sydney, 2747, Australia.
Crit Care. 2022 Aug 13;26(1):247. doi: 10.1186/s13054-022-04115-9.
Evaluating left atrial pressure (LAP) solely from the left ventricular preload perspective is a restrained approach. Accurate assessment of LAP is particularly relevant when pulmonary congestion and/or right heart dysfunction are present since it is the pressure most closely related to pulmonary venous pressure and thus pulmonary haemodynamic load. Amalgamation of LAP measurement into assessment of the 'transpulmonary circuit' may have a particular role in differentiating cardiac failure phenotypes in critical care. Most of the literature in this area involves cardiology patients, and gaps of knowledge in application to the bedside of the critically ill patient remain significant. Explored in this review is an overview of left atrial physiology, invasive and non-invasive methods of LAP measurement and their potential clinical application.
仅从左心室前负荷的角度评估左心房压力(LAP)是一种受限的方法。当存在肺充血和/或右心功能障碍时,准确评估 LAP 尤为重要,因为它与肺静脉压力最密切相关,因此与肺血流动力学负荷最密切相关。将 LAP 测量合并到“肺循环”评估中可能在区分危重病患者的心力衰竭表型方面具有特殊作用。该领域的大多数文献都涉及心脏病患者,并且在应用于危重病患者床边方面仍然存在重大知识差距。本综述探讨了左心房生理学、LAP 测量的有创和无创方法及其潜在的临床应用。