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[骨科与创伤学研究实验室]

[The Orthopaedic and Traumatology Research Laboratory].

作者信息

Hinsenkamp M, Burny F, Donkerwolcke M, Schuind F, Collard J F

机构信息

Laboratoire de Recherche en Orthopédie Traumatologie (LROT), Service d'Orthopédie-Traumatologie, Hôpital Erasme, Bruxelles.

出版信息

Rev Med Brux. 2011;32(6 Suppl):S16-22.

Abstract

The history of the Orthopaedics and Traumatology Research Laboratory (LROT) is summarized during the last thirty years. The approach, initially focused on bone biomechanics and strength of materials, underwent a rapid diversification as expressed by the list of research topics: monitoring of bone healing; bone strains measurements for different level of activities including microgravity and prevention of disuse osteoporosis; biological effects of electromagnetic fields; evolution of the viscoelastic properties of the callus during bone healing; improvement of the osteoinductive properties of bone substitutes produced by the Tissues Bank of the University Hospital Erasme; Kashin-Beck disease; SICOT telediagnostic, and biomechanics of threaded implants. Those topics, event the most fundamental ones, have immediate significant clinical applications allowing a decrease of the morbidity and an acceleration of the rehabilitation of the patients. The results show the need of multidisciplinary collaborations coordinated around one autonomous laboratory, able to handle specific protocols requiring a dedicate environment.

摘要

本文总结了骨科与创伤学研究实验室(LROT)在过去三十年的历史。该实验室最初专注于骨生物力学和材料强度,随着研究主题的不断扩展,其研究方向迅速多元化,这些主题包括:骨愈合监测;不同活动水平下的骨应变测量,其中涵盖微重力环境以及预防废用性骨质疏松;电磁场的生物学效应;骨愈合过程中骨痂粘弹性特性的演变;伊拉斯谟大学医院组织库生产的骨替代物骨诱导特性的改善;大骨节病;SICOT远程诊断以及螺纹植入物的生物力学。这些主题,即使是最基础的主题,都具有直接且重要的临床应用价值,能够降低患者的发病率并加速康复进程。结果表明,需要围绕一个自主实验室进行多学科协作,该实验室应能够处理需要特定环境的专门方案。

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