University of Cork, Cork, Ireland.
Perspect Public Health. 2012 Jan;132(1):39-42. doi: 10.1177/1757913911431038.
To estimate the prevalence of limited health literacy in patients receiving clozapine for schizophrenia. To develop and produce a pharmacist-designed clozapine patient information leaflet (PIL) which has a higher readability score than the company-produced PIL.
This was a cross sectional prevalence study.
Ethical approval for the study was granted by the local ethics committee. Patients, over 18 years, attending the Clozapine Clinic of a Cork urban teaching hospital, were asked to participate in the study. Demographics such as gender, age, employment and smoking status, were gathered from all participants. The total daily clozapine dose, duration of clozapine treatment, and information regarding the clozapine DVD was also noted. The Rapid Estimate of Adult Literacy in Medicine (REALM) health literacy (HL) screening tool was then administered to each patient. A user-friendly PIL on clozapine was designed by the pharmacist, which was assessed for readability and compared to the company-produced PIL using the FRES and FKGL. Data were analysed using SPSS Version 15.
Forty patients (65% male, 95% unemployed and 70% smokers) of average age 38.0 years (+/- 11.2) completed the REALM. The average score was 60.6 (+/- 8.7). Twenty-nine patients (72.5%) were found to have "adequate" health literacy. The remaining eleven patients were found to have either "marginal" or "low" health literacy. The pharmacist-designed PIL would have been readable by 95% of the study population, in contrast to 72.5% with the company-designed PIL.
More than a quarter of the population were found to have marginal or low health literacy. Patient information should be matched to the health literacy level of the target population.
评估接受氯氮平治疗精神分裂症的患者中有限健康素养的患病率。 开发并制作一份药剂师设计的氯氮平患者信息传单（PIL），其可读性评分高于公司生产的 PIL。
这是一项横断面患病率研究。
当地伦理委员会批准了该研究的伦理许可。 邀请在科克市教学医院的氯氮平诊所就诊的 18 岁以上患者参与研究。 从所有参与者中收集了人口统计学信息，如性别、年龄、职业和吸烟状况。 还记录了患者的氯氮平总日剂量、氯氮平治疗持续时间以及氯氮平 DVD 的信息。 然后对每位患者进行快速成人医学识字能力评估工具（REALM）健康素养（HL）筛查工具。 药剂师设计了一份易于使用的氯氮平 PIL，并使用 FRES 和 FKGL 对其可读性进行评估，并与公司生产的 PIL 进行比较。 使用 SPSS 版本 15 分析数据。
40 名患者（65%为男性，95%为失业者，70%为吸烟者），平均年龄为 38.0 岁（+/-11.2），完成了 REALM。 平均得分为 60.6（+/-8.7）。 29 名患者（72.5%）被认为具有“足够”的健康素养。 其余 11 名患者被发现具有“边缘”或“低”健康素养。 药剂师设计的 PIL 将能够被 95%的研究人群阅读，而公司设计的 PIL 则为 72.5%。
超过四分之一的患者被发现具有边缘或低健康素养。 患者信息应与目标人群的健康素养水平相匹配。
