Prichard A J, Colloby P, Barton R P, Heaton J M
Department of Otolaryngology, Leicester Royal Infirmary.
J Laryngol Otol. 1990 Oct;104(10):797-800. doi: 10.1017/s0022215100113921.
The term 'tumefactive fibroinflammatory lesion' has been used to describe a fibrosclerosing disorder which has a locally destructive nature but is characterized by a benign histological appearance. We report five patients, over a five year period, with such a lesion. The clinical behaviour and surgical findings suggest the lesion to be an invasive malignancy. However, the histological appearance of an admixture of chronic inflammatory cells and fibrosis is consistent with a benign condition. We recommend surgical excision of the lesion as the mainstay of treatment; other studies report the use of steroids and radiotherapy.
术语“肿胀性纤维炎性病变”已被用于描述一种具有局部破坏性但组织学表现为良性的纤维硬化性疾病。我们报告了在五年期间患有这种病变的五名患者。临床行为和手术发现提示该病变为侵袭性恶性肿瘤。然而，慢性炎性细胞和纤维化混合的组织学表现与良性情况相符。我们建议以手术切除该病变作为主要治疗方法；其他研究报告了使用类固醇和放疗。
