Krinke G, Ullmann L, Sachsse K, Hess R
Agents Actions. 1979 Jun;9(2):227-31. doi: 10.1007/BF02024740.
The nerve fibres of largest diameter and of greatest length are considered to be the most vulnerable to triorthocresyl phosphate (TOCP). In this study, the differential vulnerability of the particular sciatic nerve branches was determined in the course of TOCP neuropathy and of Wallerian degeneration. The branch innervating the lateral gastrocnemius muscle, made up predominantly of large-diameter fibres, proved most susceptible to TOCP. By contrast, after proximal sciatic-nerve transection, degeneration commenced in the lateral nerve of the third digit, containing long nerve fibres of small diameter.
直径最大且长度最长的神经纤维被认为最易受到磷酸三甲苯酯（TOCP）的影响。在本研究中，在TOCP神经病变和华勒氏变性过程中确定了坐骨神经特定分支的差异易损性。支配腓肠肌外侧头的分支主要由大直径纤维组成，被证明对TOCP最敏感。相比之下，在坐骨神经近端横断后，第三趾外侧神经开始变性，该神经含有小直径的长神经纤维。
