Jiang Jin-Feng, Xu Lei, Lin Yan-Hong, Lu Jin-Hua, Chen Li-Zhi, Sun Yi-Nong
The Second Clinical Medical College of Nanjing University of CM, Nanjing 210029, Jiangsu Province, China.
Zhongguo Zhen Jiu. 2012 Mar;32(3):219-23.
To verify the anti-depression effect of acupuncture and moxibustion based on the medication with selective serotonin reuptake inhibitors (SSRIs).
Eighty cases of depression were randomly divided into an acupuncture-moxibustion-medication group (25 cases), an acupuncture-medication group (25 cases) and a medication group (30 cases). SSRIs medication was administered in all of the three groups. Complementarily, in acupuncture-moxibustion-medication group, the needling technique of qi conduction in the Governor Vessel was applied to Baihui (GV 20), Fengfu (GV 16), Dazhui (GV 14), etc. Additionally, mild moxibustion was added at Dazhui (GV 14) and Baihui (GV 20). In acupuncture-medication group, acupuncture for qi conduction in the Governor Vessel was only adopted. Hamilton Depression Scale (HAMD) was used for the evaluation of the total score, the score of each factor before and after treatment separately, and the therapeutic effects were observed among 3 groups.
Compared with medication group, the scores of the factors as retardation, sleep, and anxiety/somatization, as well as the total score were all apparently improved in the other two groups (P < 0.05, P < 0.01). Compared with acupuncture-medication group, the scores of sleep and cognition factors as well as the total score in HAMD were much improved in acupuncture-moxibustion-medication group (P < 0.05, P < 0.01). The remarkable effective rates were 100.0% (25/25), 84.0% (21/25) and 56.7% (17/30) in the three groups separately, in which, the result in acupuncture-moxibustion-medication group was superior to acupuncture-medication group (P < 0.05), and the results of these two groups were superior to medication group (both P < 0.01).
Either acupunctrure or moxibustion has a definite anti-depression effect based on SSRIs medication, but the coordination of acupuncture and moxibustion achieves a superior efficacy as compared with simple acupuncture therapy.
验证基于选择性5-羟色胺再摄取抑制剂（SSRIs）药物治疗基础上的针灸抗抑郁效果。
将80例抑郁症患者随机分为针药结合组（25例）、针灸组（25例）和药物组（30例）。三组均给予SSRIs药物治疗。针药结合组在此基础上，采用督脉导气针法针刺百会（GV 20）、风府（GV 16）、大椎（GV 14）等穴位，并在大椎（GV 14）、百会（GV 20）加用温和灸。针灸组仅采用督脉导气针法针刺。分别于治疗前后采用汉密尔顿抑郁量表（HAMD）评定总分及各因子分，观察三组疗效。
与药物组比较，其他两组迟缓、睡眠、焦虑/躯体化等因子分及总分均明显改善（P < 0.05，P < 0.01）。与针灸组比较，针药结合组睡眠、认知因子分及HAMD总分改善更明显（P < 0.05，P < 0.01）。三组显效率分别为100.0%（25/25）、84.0%（21/25）、56.7%（17/30），针药结合组疗效优于针灸组（P < 0.05），两组均优于药物组（P均< 0.01）。
基于SSRIs药物治疗基础上，针灸均有明确的抗抑郁作用，但针药结合的疗效优于单纯针灸治疗。
