Rosenfeld Hannah E, Tsokos Michael, Byard Roger W
The University of Adelaide Medical School, Adelaide, SA 5005, Australia.
J Forensic Sci. 2012 Sep;57(5):1336-8. doi: 10.1111/j.1556-4029.2012.02140.x. Epub 2012 Apr 3.
To evaluate the association between obesity and pulmonary thromboembolism (PTE) in a forensic context, 160 autopsy cases of fatal PTE were compared with age- and gender-matched controls. The mean age of cases was 66 years (range 26-98 years; M/F 74:86). The mean body mass index (BMI) of cases with PTE was 30.88 (range 14.95-79.51), which was significantly higher than in the controls (mean BMI = 25.33; range 12.49-61.84) (p < 0.0001). Comparing the group with PTE with controls showed that five (3.1%) compared to 20 (12.5%) were underweight, 39 (24.4%) compared to 67 (41.88%) were of normal weight, 49 (30.63%) compared to 43 (26.88%) were overweight, 43 (26.88%) compared to 24 (15%) were obese, and 24 (15.0%) compared to six (3.75%) were morbidly obese. In each category of above-normal BMIs, there were significantly greater numbers in the groups with PTE: overweight (p < 0.01), obese (p < 0.001), and morbidly obese (p < 0.0001).
为了在法医学背景下评估肥胖与肺血栓栓塞症（PTE）之间的关联，将160例致命性PTE尸检病例与年龄和性别匹配的对照组进行了比较。病例的平均年龄为66岁（范围26 - 98岁；男/女比例为74:86）。PTE病例的平均体重指数（BMI）为30.88（范围14.95 - 79.51），显著高于对照组（平均BMI = 25.33；范围12.49 - 61.84）（p < 0.0001）。将PTE组与对照组进行比较发现，体重过轻的比例分别为5例（3.1%）和20例（12.5%），正常体重的比例分别为39例（24.4%）和67例（41.88%），超重的比例分别为49例（30.63%）和43例（26.88%），肥胖的比例分别为43例（26.88%）和24例（15%），病态肥胖的比例分别为24例（15.0%）和6例（3.75%）。在BMI高于正常的每个类别中，PTE组的人数均显著更多：超重（p < 0.01）、肥胖（p < 0.001）和病态肥胖（p < 0.0001）。
