Division of Neurology, Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Sask., Canada. jft084 @ mail.usask.ca
Eur Neurol. 2010;64(3):134-9. doi: 10.1159/000316656. Epub 2010 Jul 22.
To explore the prevalence of overweight and obesity in patients with migraine.
Previous studies support the concept that obesity is an exacerbating factor for migraine. Also, some studies have found an increased frequency of obesity and overweight in migraine patients compared to the normal population.
We studied 1,371 patients with migraine and 612 controls. The migraine population was matched by gender with a healthy control group.
Mean age of patients with migraine was 38.0 +/- 13.3 years and in the controls it was 34.8 +/- 12.1 years. The percentage of females in both groups was similar (migraine 81.6% vs. control 83.3%, p = 0.40). The distribution of body mass index (BMI) in migraine patients and controls was as follows: underweight patients (BMI <18.5) 3.1% migraine versus controls 1.5%; normal (BMI 18.5-24.9) 44.8% migraine versus controls 47.1%; overweight (BMI 25-29.9) 38.3% migraine versus controls 33.7%; obese (BMI 30-34.5) 10.3% migraine versus controls 13.6%; morbidly obese (BMI 35) 3.4% migraine versus controls 4.2%. Overweight and obesity in migraine patients versus controls were statistically significant. No association was found between the disability and severity of migraine and BMI.
This study did not find associations between severity or disability of migraine and BMI.
探讨偏头痛患者超重和肥胖的患病率。
先前的研究支持肥胖是偏头痛加重因素的概念。此外，一些研究发现与正常人群相比，偏头痛患者中肥胖和超重的频率增加。
我们研究了 1371 名偏头痛患者和 612 名对照者。偏头痛人群按性别与健康对照组相匹配。
偏头痛患者的平均年龄为 38.0 ± 13.3 岁，对照组为 34.8 ± 12.1 岁。两组女性的比例相似（偏头痛 81.6%对对照组 83.3%，p = 0.40）。偏头痛患者和对照组的体重指数（BMI）分布如下：体重不足患者（BMI <18.5）偏头痛为 3.1%，对照组为 1.5%；正常（BMI 18.5-24.9）偏头痛为 44.8%，对照组为 47.1%；超重（BMI 25-29.9）偏头痛为 38.3%，对照组为 33.7%；肥胖（BMI 30-34.5）偏头痛为 10.3%，对照组为 13.6%；病态肥胖（BMI 35）偏头痛为 3.4%，对照组为 4.2%。偏头痛患者与对照组相比，超重和肥胖具有统计学意义。未发现偏头痛的残疾和严重程度与 BMI 之间存在相关性。
本研究未发现偏头痛的严重程度或残疾与 BMI 之间存在相关性。
