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[颞浅动脉与大脑中动脉吻合术治疗双侧颈内动脉闭塞性疾病伴痴呆]

[Anastomosis of the superficial temporal artery to the middle cerebral artery for occlusive disease of the bilateral internal carotid arteries with dementia].

作者信息

Abiko S, Matsunaga T, Yamashita T, Fujii M, Aoki H

机构信息

Department of Neurosurgery, Yamaguchi University Hospital, Ube, Japan.

出版信息

No Shinkei Geka. 1990 Nov;18(11):1047-52.

PMID:2247199
Abstract

Two cases are reported of occlusive disease of the bilateral internal carotid arteries with dementia in which the anastomosis of the superficial temporal artery to the middle cerebral artery (STA-MCA bypass) resulted in marked improvement in clinical aspects. One patient was a 29-year-old male who complained of transient weakness of the extremities and memory impairment. Computerized tomography (CT) scans showed multiple small infarctions, while cerebral angiography demonstrated findings of Moya-like disease. The cognitive function tests were subnormal and the study of cerebral blood flow (CBF study) showed diffuse low flow in both hemispheres. Based on his clinical symptoms and CBF study, the STA-MCA bypass was performed on both sides in two stages without complications. Postoperatively, his clinical symptoms and cognitive function improved gradually, in accordance with increased CBF in both hemispheres. Six months after the operation, cognitive function tests were within normal limits. Another patient was a 61-year-old hypertensive male who complained of motor weakness, impairment of memory and urinary incontinence. CT scans showed multiple small infarctions, while cerebral angiography revealed occlusion of both internal carotid arteries at the cervical portion. The cognitive function was at the pre-dementia level, and CBF study revealed diffuse low flow in both hemispheres. Based on the clinical symptoms and CBF study, the STA-MCA bypass was performed on both sides in two stages. Postoperatively, clinical symptoms and cognitive function markedly improved. From our results, the diagnosis of vascular dementia, and indications for the use of STA-MCA bypass in this category of patients are discussed.

摘要

报告了两例双侧颈内动脉闭塞性疾病伴痴呆的病例,其中颞浅动脉与大脑中动脉吻合术(颞浅动脉-大脑中动脉搭桥术)使临床症状有显著改善。一例患者为29岁男性,主诉肢体短暂无力和记忆力减退。计算机断层扫描(CT)显示多处小梗死灶,而脑血管造影显示有烟雾样病的表现。认知功能测试结果低于正常水平,脑血流研究(CBF研究)显示双侧半球弥漫性低血流。根据其临床症状和CBF研究,分两期对双侧进行了颞浅动脉-大脑中动脉搭桥术,无并发症发生。术后,其临床症状和认知功能逐渐改善,与双侧半球CBF增加一致。术后6个月,认知功能测试结果在正常范围内。另一例患者为61岁高血压男性,主诉运动无力、记忆力减退和尿失禁。CT扫描显示多处小梗死灶,而脑血管造影显示双侧颈内动脉在颈部闭塞。认知功能处于痴呆前期水平,CBF研究显示双侧半球弥漫性低血流。根据临床症状和CBF研究,分两期对双侧进行了颞浅动脉-大脑中动脉搭桥术。术后,临床症状和认知功能明显改善。根据我们的结果,讨论了血管性痴呆的诊断以及此类患者使用颞浅动脉-大脑中动脉搭桥术的适应证。

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