Eguchi T, Mayanagi Y, Takakura K
No Shinkei Geka. 1983 Oct;11(10):1037-46.
The combined one-stage operations, STA-MCA anastomosis and internal carotid artery (ICA) ligation (or trapping) were carried out in 11 cases (Age): 18-79 yrs, Av.: 45.8 yrs) of ICA aneurysms which were inaccessible for a direct operation because of their locations and sizes. First the STA-MCA anastomosis was performed under general anesthesia. Then the patient was awaken and thereafter under local anesthesia the ICA was temporarily clamped for 30 min. under induced hypotension to check whether any ischemic signs appeared. This was followed by proximal ICA ligation when no ischemic signs were observed. In all 11 cases, the anastomosis was patent. The aneurysms disappeared. Neither cerebral ischemia nor rebleeding from the aneurysms was seen during the long follow-up. The mean value of the bypass flow was 119 m/min which was twice as much as that in the cases of other occlusive cerebrovascular diseases and which was about one third of the blood flow of the ICA. Cerebral blood flow measurements through 133Xe inhalation method revealed that there was no difference in rCBF values between the operated and non-operated sides and that their values were within normal limits. The postoperative blood pressure was unchanged in 42% of our 11 cases, temporarily elevated and thereafter normalized in 33% and persistently elevated in 25%. Ophthalmodynamometry showed that the pressure of the central retinal artery decreased postoperatively in a degree of 5-10% in comparison to the non-operated side. No visual impairment was observed postoperatively (except case 3, see the text). These combined operations, STA-MCA anastomosis and ICA ligation were beneficial in preventing the potential postoperative cerebral ischemia. Intra-arterial pressure measurements of the STA and MCA suggested that the one-stage operations of these two procedures are better than the two-stage operations for the patency of the anastomosis because the pressure gradient between the donor and recipient vessels is increased (from 10.3 mmHg to 49.3 mmHg) by this technique. Temporary ICA clamp for 30 min. under induced hypotension in local anesthesia is useful to check whether the one-stage operations can be tolerated or not. EC/IC bypass with an interposed saphenous vein graft is a more beneficial surgical technique than a routine STA-MCA anastomosis, because an immediate and larger amount of bypass flow can be obtained.
对11例(年龄18 - 79岁,平均45.8岁)因位置和大小无法直接手术的颈内动脉(ICA)动脉瘤患者进行了联合一期手术,即颞浅动脉 - 大脑中动脉(STA - MCA)吻合术和颈内动脉结扎(或夹闭)术。首先在全身麻醉下进行STA - MCA吻合术。然后唤醒患者,之后在局部麻醉下于诱导性低血压状态下暂时夹闭颈内动脉30分钟,以检查是否出现任何缺血征象。当未观察到缺血征象时,接着进行颈内动脉近端结扎。11例患者中,吻合口均通畅。动脉瘤消失。在长期随访期间,未发现脑缺血或动脉瘤再出血情况。搭桥血流量的平均值为119ml/min,是其他闭塞性脑血管疾病病例的两倍,约为颈内动脉血流量的三分之一。通过吸入133Xe法测量脑血流量显示,手术侧和未手术侧的相对脑血流量(rCBF)值无差异,且均在正常范围内。11例患者中,42%术后血压无变化,33%暂时升高后恢复正常,25%持续升高。视网膜动脉压测量显示,与未手术侧相比,术后视网膜中央动脉压力下降5% - 10%。术后未观察到视力损害(病例3除外,见正文)。这些联合手术,即STA - MCA吻合术和颈内动脉结扎术,有利于预防潜在的术后脑缺血。对颞浅动脉和大脑中动脉进行动脉内压力测量表明,这两种手术的一期手术在吻合口通畅方面优于二期手术,因为该技术使供体和受体血管之间的压力梯度增加(从10.3mmHg增至49.3mmHg)。在局部麻醉下诱导性低血压状态下暂时夹闭颈内动脉30分钟,有助于检查一期手术是否可耐受。采用大隐静脉移植的颅外 - 颅内(EC/IC)搭桥术是一种比常规STA - MCA吻合术更有益的手术技术,因为可立即获得更大的搭桥血流量。