Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Gynecol Oncol. 2012 Jun;125(3):705-11. doi: 10.1016/j.ygyno.2012.03.045. Epub 2012 Apr 1.
To investigate the effects of a pelvic floor rehabilitation program (PFRP) on pelvic floor function and quality of life (QoL) in gynecological cancer survivors in a prospective, randomized, controlled trial.
Thirty-four patients with gynecological cancers recruited between July 2009 and December 2009 were randomly allocated into two groups: a PFRP group (n=17), who participated in a 4-week PFRP exercise program, and a non-PFRP group (n=17), who received the usual health care. The pelvic floor strength, the motor evoked potentials (MEPs) elicited by sacral and transcranial magnetic stimulation, the pelvic floor questionnaire, and the scores on two QoL questionnaires, (QLQ)-C30 and QLQ-CX 24, from the European Organization for Research and Treatment of Cancer (EORTC) were evaluated to assess changes in pelvic floor function and QoL before and after the exercise program.
Twenty four patients (12 from each group) completed the exercise program. The PFRP group improved in pelvic floor strength (mean difference (MD)=14.22, t(9)=2.389, P=0.036) and sexual functioning. The PFRP group also improved in physical and sexual function compared with the non-PFRP group.
The results suggest that the PFRP improved pelvic floor dysfunction and QoL of gynecological cancer patients. A larger randomized controlled trial is planned.
前瞻性随机对照试验研究盆腔康复计划（PFRP）对妇科癌症幸存者盆底功能和生活质量（QoL）的影响。
2009 年 7 月至 2009 年 12 月期间，招募了 34 名妇科癌症患者，随机分为两组：PFRP 组（n=17），参加了为期 4 周的 PFRP 锻炼计划；非 PFRP 组（n=17），接受常规保健。评估盆底力量、骶骨和经颅磁刺激诱发的运动诱发电位（MEPs）、盆底问卷以及欧洲癌症研究与治疗组织（EORTC）的两个生活质量问卷（QLQ）-C30 和 QLQ-CX 24 的评分，以评估锻炼计划前后盆底功能和 QoL 的变化。
24 名患者（每组 12 名）完成了锻炼计划。PFRP 组盆底力量改善（平均差异（MD）=14.22，t（9）=2.389，P=0.036）和性功能改善。与非 PFRP 组相比，PFRP 组在身体和性功能方面也有所改善。
结果表明，PFRP 改善了妇科癌症患者的盆底功能障碍和生活质量。计划进行更大规模的随机对照试验。
