Smith M S, Williams D E, Worley S D
Department of Chemistry, Auburn University, Alabama 36849.
Poult Sci. 1990 Sep;69(9):1590-4. doi: 10.3382/ps.0691590.
Five organic N-halamine compounds (combined halogen disinfectants) were compared for their bactericidal activities against Salmonella typhimurium under controlled pH and temperature. All five compounds were effective as bactericides in demand-free buffers ranging from pH 5.0 to 9.0 and treatment temperatures from 4 to 48 C. The range of contact times necessary for a 99.9999% inactivation of viable cells was from .22 to 29 min, depending on the halogen concentration, temperature, and pH of the demand-free buffer. Two of the compounds (3-chloro-4,4-dimethyl-2-oxazolidinone and 1,3-dichloro-4,4,5,5-tetramethyl-2-imidazolidinone) were found to have considerable promise in high-temperature applications, and a third compound (1-bromo-3-chloro-4,4,5,5-tetramethyl-2-imidazolidinone) was more suitable for low-temperature treatments.
在可控的pH值和温度条件下,对五种有机N-卤胺化合物(复合卤素消毒剂)针对鼠伤寒沙门氏菌的杀菌活性进行了比较。在pH值为5.0至9.0的无需求缓冲液以及4至48摄氏度的处理温度范围内,所有五种化合物均具有杀菌效果。使活菌达到99.9999%灭活所需的接触时间范围为0.22至29分钟,具体取决于无需求缓冲液中的卤素浓度、温度和pH值。发现其中两种化合物(3-氯-4,4-二甲基-2-恶唑烷酮和1,3-二氯-4,4,5,5-四甲基-2-咪唑烷酮)在高温应用中具有很大潜力,而第三种化合物(1-溴-3-氯-4,4,5,5-四甲基-2-咪唑烷酮)更适合低温处理。