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[胫骨坡度增加是否会降低单髁膝关节假体的磨损率?一项体外研究]

[Does increased tibial slope reduce the wear rate of unicompartmental knee prostheses? An in vitro investigation].

作者信息

Weber P, Schröder C, Utzschneider S, Schmidutz F, Jansson V, Müller P E

机构信息

Orthopädische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

出版信息

Orthopade. 2012 Apr;41(4):298-302. doi: 10.1007/s00132-011-1857-8.

Abstract

INTRODUCTION

Unicompartmental knee arthroplasty (UKA) has become a standard procedure with good clinical outcome in patients with isolated medial osteoarthritis of the knee. However, the survival rates of UKA are still inferior compared to that of total knee arthroplasty. Aseptic loosening and wear are responsible for more than 50% of revisions. Therefore, this study evaluated the influence of the tibial slope on the wear rate in a medial UKA.

MATERIALS AND METHODS

The wear rate of a medial mobile-bearing UKA (Univation® Aesculap, Tuttlingen, Deutschland) was evaluated according to the ISO 14243-1:2002(E) norm with a customized four-station servo-hydraulic knee wear simulator (EndoLab, Thansau, Germany). In the first group, the prostheses was medially implanted with 0° slope (n = 3) and in the second group the prostheses was medially implanted with 8° slope (n = 3). The lateral side was kept constant with 0° in both groups. For each implant, a total of 5.0 million cycles was performed and after every 0.5 million cycles the gravimetric wear rate was determined.

RESULTS

The wear rate in the 0° slope group was 3.46 ± 0.59 mg/million cycles and therefore significantly higher than in the 8° slope group with 0.99 ± 0.42 mg/million cycles (p < 0.01).

DISCUSSION

An increase in the tibial slope leads to a reduced wear rate in a mobile-bearing UKA. Therefore, at least for this mobile-bearing UKA a higher tibial slope seems favorable to reduce the wear. However, before an optimal position of the tibial slope can be recommended, further investigations are required to evaluate the influence of the tibial slope on other factors, such as the ligament tension or the strain on the lateral compartment.

摘要

引言

单髁膝关节置换术(UKA)已成为治疗膝关节孤立性内侧骨关节炎患者的标准手术,临床效果良好。然而,与全膝关节置换术相比,UKA的生存率仍然较低。无菌性松动和磨损导致了超过50%的翻修手术。因此,本研究评估了胫骨坡度对内侧UKA磨损率的影响。

材料与方法

根据ISO 14243-1:2002(E)标准,使用定制的四站伺服液压膝关节磨损模拟器(德国坦绍的EndoLab)评估内侧活动平台UKA(德国图特林根的Univation® Aesculap)的磨损率。第一组中,假体以0°坡度内侧植入(n = 3),第二组中,假体以8°坡度内侧植入(n = 3)。两组的外侧均保持0°不变。对于每个植入物,总共进行500万次循环,每50万次循环后测定重量磨损率。

结果

0°坡度组的磨损率为3.46±0.59毫克/百万次循环,因此显著高于8°坡度组的0.99±0.42毫克/百万次循环(p < 0.01)。

讨论

胫骨坡度增加会导致活动平台UKA的磨损率降低。因此,至少对于这种活动平台UKA,较高的胫骨坡度似乎有利于减少磨损。然而,在推荐胫骨坡度的最佳位置之前,需要进一步研究以评估胫骨坡度对其他因素的影响,如韧带张力或外侧间室的应变。

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