Quast U, Dutreix A, Broerse J J
Department of Radiotherapy, University Hospital, Essen, F.R.G.
Radiother Oncol. 1990;18 Suppl 1:158-62. doi: 10.1016/0167-8140(90)90200-g.
Clear and complete documentation of the physical parameters of total body irradiation (TBI) is one of the essential requirements for the evaluation and improvement of the clinical results of TBI. Concerning the dosimetric aspects of TBI, a number of recommendations have been formulated with emphasis on basic dosimetry, patient dosimetry and dose specification. The dosimeters should be calibrated regularly with reference to the absorbed dose in water. Depth dose measurements should be performed in water equivalent phantoms of specified dimensions. It has been strongly suggested to measure the absorbed dose at the surface of the patient at 8 different regions at the entry and exit of the beam under TBI conditions. The reference dose to the patient should be specified as the total dose to mid abdomen at the height of the umbilicus. As an independent parameter, the lung dose should be specified as the mean dose in the central region of the shielded part of both lungs. Recent, more complete, information on the physical and dosimetric aspects of TBI will be incorporated in the registry of the European Bone Marrow Transplant Group (EBMT). A cooperation has been established between the EBMT and the European Late Effects Project Group (EULEP) to study the development of late effects in man caused by ionising radiation.
全身照射（TBI）物理参数的清晰完整记录是评估和改善TBI临床结果的基本要求之一。关于TBI的剂量学方面，已经制定了一些建议，重点是基本剂量学、患者剂量学和剂量规范。剂量计应定期参照水中吸收剂量进行校准。深度剂量测量应在规定尺寸的水等效体模中进行。强烈建议在TBI条件下，在束流的入口和出口处的8个不同区域测量患者表面的吸收剂量。患者的参考剂量应规定为脐部高度处中腹部的总剂量。作为一个独立参数，肺部剂量应规定为双肺屏蔽部分中心区域的平均剂量。关于TBI物理和剂量学方面的最新、更完整的信息将纳入欧洲骨髓移植组（EBMT）的登记册。EBMT与欧洲晚期效应项目组（EULEP）已经建立合作，以研究电离辐射对人类造成的晚期效应的发展情况。
