González Rodríguez M D, Sosa Henríquez M, Limiñana Cañal J M, Betancor León P
Universidad de Las Palmas de Gran Canaria, Colegio Universitario de Las Palmas.
Rev Clin Esp. 1990 May;186(9):436-9.
We have tried to experimentally determine what effect castration is going to have on rats bone and on the main mineral bone regulatory hormones. Twenty ovariectomized female rats and their age and weight matched controls were used. Parathormone, calcitonin, osteocalcin and serum calcium levels were determined as well as mineral bone content and head of femur density. Castration produces, in rat, a marked decrease in circulating calcitonin, parathormone (PTH) and bone density, with no changes in mineral bone concentration. Finally, castration produces a slight increase in osteocalcin serum levels although without a statistical value.
我们试图通过实验确定去势对大鼠骨骼及主要骨矿物质调节激素会产生何种影响。我们使用了20只去卵巢的雌性大鼠及其年龄和体重匹配的对照组。测定了甲状旁腺激素、降钙素、骨钙素和血清钙水平，以及骨矿物质含量和股骨头部密度。去势使大鼠体内循环的降钙素、甲状旁腺激素（PTH）和骨密度显著降低，而骨矿物质浓度没有变化。最后，去势使骨钙素血清水平略有升高，不过无统计学意义。
