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接受不育治疗患者的睾丸钙化与肿瘤形成

Testicular calcifications and neoplasia in patient treated for subfertility.

作者信息

Salisz J A, Goldman K A

机构信息

Department of Urology, William Beaumont Hospital, Royal Oak, Michigan.

出版信息

Urology. 1990 Dec;36(6):557-60. doi: 10.1016/0090-4295(90)80202-x.

DOI:10.1016/0090-4295(90)80202-x
PMID:2247930
Abstract

A subfertile male with a history of left cryptorchism underwent scrotal ultrasound that revealed stippled calcifications, without associated mass, in the right testicle. Six months later, while on a regimen of clomiphene citrate, a testicular tumor became palpable. This was sonographically confirmed to be surrounding the calcifications. Testicular calcifications are most commonly associated with benign conditions. We review the literature regarding their relationship to neoplasms and the significance of the ultrasonic findings. Furthermore, this is the sixth reported case of testicular tumor developing during hormonal treatment for oligospermia. Although these cases may be circumstantial, closer surveillance and screening ultrasound may be indicated for subfertile males taking clomiphene citrate.

摘要

一名有左侧隐睾病史的男性不育患者接受了阴囊超声检查,结果显示右侧睾丸有散在钙化灶,无相关肿块。六个月后,在服用枸橼酸氯米芬期间,可触及睾丸肿瘤。超声检查证实该肿瘤围绕钙化灶。睾丸钙化最常见于良性疾病。我们回顾了关于它们与肿瘤的关系以及超声检查结果意义的文献。此外,这是第六例报道的在少精子症激素治疗期间发生睾丸肿瘤的病例。尽管这些病例可能是偶然的,但对于服用枸橼酸氯米芬的男性不育患者,可能需要更密切的监测和筛查超声检查。

相似文献

1
Testicular calcifications and neoplasia in patient treated for subfertility.接受不育治疗患者的睾丸钙化与肿瘤形成
Urology. 1990 Dec;36(6):557-60. doi: 10.1016/0090-4295(90)80202-x.
2
[Testicular microlithiasis and testicular cancer].[睾丸微结石症与睾丸癌]
Arch Esp Urol. 2003 Jun;56(5):521-4.
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Case report: the ultrasound appearances of testicular microlithiasis ('snow storm' testis): a case complicated by testicular seminoma.病例报告:睾丸微结石症(“暴风雪”样睾丸)的超声表现:1例合并睾丸精原细胞瘤的病例
Clin Radiol. 1993 Jan;47(1):65-7. doi: 10.1016/s0009-9260(05)81220-6.
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Testicular microlithiasis: a benign condition with a malignant association.睾丸微结石症:一种伴有恶性关联的良性病症。
J Clin Ultrasound. 1996 May;24(4):197-202. doi: 10.1002/(SICI)1097-0096(199605)24:4<197::AID-JCU6>3.0.CO;2-A.
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Testicular microlithiasis associated with seminoma: Gray-scale and color Doppler ultrasound findings.睾丸微结石症合并精原细胞瘤:灰阶及彩色多普勒超声表现
Urol Int. 1996;57(4):255-8. doi: 10.1159/000282928.
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Ultrasonographic findings of testicular microlithiasis associated with intratubular germ cell neoplasia.与管内生殖细胞肿瘤相关的睾丸微结石症的超声检查结果
Urology. 1991 Jan;37(1):66-8. doi: 10.1016/0090-4295(91)80081-h.
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Testicular simple cyst and teratoma: asynchronous bilateral occurrence within the first year of life.睾丸单纯性囊肿和畸胎瘤:出生后第一年内双侧异步发生。
Urology. 1999 Aug;54(2):366. doi: 10.1016/s0090-4295(99)00059-x.
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Testicular microlithiasis: association with male infertility.睾丸微石症:与男性不育的关联
J Clin Ultrasound. 1998 May;26(4):195-8. doi: 10.1002/(sici)1097-0096(199805)26:4<195::aid-jcu3>3.0.co;2-8.
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[Three cases of cystic testicular disease: simple cyst of the testis, cyst of the tunica alubuginea and mature cystic teratoma].[三例睾丸囊性疾病:睾丸单纯囊肿、白膜囊肿和成熟囊性畸胎瘤]
Hinyokika Kiyo. 1993 Mar;39(3):265-8.
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Adenomatoid tumor of epididymis simulating benign cyst on scrotal ultrasound.
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Oncotarget. 2017 Feb 7;8(6):10714-10725. doi: 10.18632/oncotarget.12956.
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Testicular calcification and microlithiasis: association with primary intra-testicular malignancy in 3,477 patients.睾丸钙化与微结石症:3477例患者中与原发性睾丸内恶性肿瘤的关联
Eur Radiol. 2007 Feb;17(2):363-9. doi: 10.1007/s00330-006-0296-0. Epub 2006 May 18.
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Testicular microlithiasis heralding mixed germ cell tumor of the testis in a boy.睾丸微结石症预示着一名男孩患睾丸混合性生殖细胞肿瘤。
J Endocrinol Invest. 2006 Jan;29(1):82-5. doi: 10.1007/BF03349182.
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Testicular microlithiasis: clinical significance and review of the literature.睾丸微石症:临床意义及文献综述
Eur Radiol. 2003 Dec;13(12):2567-76. doi: 10.1007/s00330-003-2014-5. Epub 2003 Oct 3.