Geavlete B, Mulţescu R, Moldoveanu C, Stănescu F, Jecu M, Geavlete P
Clinica de Urologie, Spitalul Clinic de Urgenţă "Sfântul Ioan", Bucureşti, România.
Chirurgia (Bucur). 2012 Jan-Feb;107(1):89-94.
The trial evaluated a new endoscopic treatment alternative for large benign prostatic hyperplasia (BPH) cases, the bipolar plasma enucleation of the prostate (BPEP), in terms of surgical efficiency, safety and short-term postoperative results.
A total of 30 patients with prostates larger than 80 ml were included in the study. All cases were investigated preoperatively and at 1 and 3 months after surgery by international prostate symptoms score (IPSS), quality of life score (QoL), maximum flow rate (Q(max)) and abdominal and transrectal ultrasonography.
All procedures were successfully performed. The enucleation and morcellation times were 69.8 minutes and 18.5 minutes, while the morcellated tissue weight was 77 grams. The mean hemoglobin drop was 0.8 g/dl and the mean catheterization period and hospital stay were 26.5 hours and 2.3 days. The rate of early irritative symptoms was 10%. At 1 and 3 months, significant improvements were determined concerning the IPSS (5.3 and 4.8), QoL (1.2 and 1.1) and Q(max) (25.9 and 25.1 ml/s).
BPEP represents a promising endoscopic approach in large BPH cases, characterized by good surgical efficacy, reduced morbidity, fast postoperative recovery and satisfactory follow-up parameters.
本试验评估了一种针对大型良性前列腺增生(BPH)病例的新型内镜治疗方法——前列腺双极等离子剜除术(BPEP),涉及手术效率、安全性及术后短期效果。
本研究共纳入30例前列腺体积大于80毫升的患者。所有病例在术前以及术后1个月和3个月时,通过国际前列腺症状评分(IPSS)、生活质量评分(QoL)、最大尿流率(Q(max))以及腹部和经直肠超声进行调查。
所有手术均成功完成。剜除和粉碎时间分别为69.8分钟和18.5分钟,粉碎组织重量为77克。平均血红蛋白下降0.8克/分升,平均导尿时间和住院时间分别为26.5小时和2.3天。早期刺激性症状发生率为10%。在术后1个月和3个月时,IPSS(分别为5.3和4.8)、QoL(分别为1.2和1.1)和Q(max)(分别为25.9和25.1毫升/秒)均有显著改善。
BPEP是大型BPH病例中一种有前景的内镜治疗方法,具有良好的手术疗效、较低的发病率、术后恢复快以及令人满意的随访参数。