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产褥期自身免疫性肝炎。

Autoimmune hepatitis in the postpartum period.

机构信息

Department of Gastroenterology, Numune Research and Education Hospital, Yazgan sokak 21/12 Cebeci, Ankara, Turkey.

出版信息

Clin Res Hepatol Gastroenterol. 2012 Aug;36(4):391-3. doi: 10.1016/j.clinre.2012.02.006. Epub 2012 Apr 3.

Abstract

AIM

Autoimmune hepatitis (AIH) presenting primarily in the postpartum period has rarely been reported.

METHODS

The medical data of 58 female patients diagnosed with AIH was assessed.

RESULTS

In the study population, three (5.1%) patients were diagnosed postpartum. Based on clinical, laboratory and liver biopsy findings, two of these patients were considered to have subclinical AIH and were diagnosed by disease flare after delivery. The remaining patient was considered as new onset of AIH in the postpartum period.

CONCLUSIONS

AIH can present in the postpartum and should be actively considered among the differential diagnosis if liver dysfunction is observed after delivery.

摘要

目的

产后起病的自身免疫性肝炎(AIH)鲜有报道。

方法

评估了 58 名女性 AIH 患者的医学数据。

结果

研究人群中,有 3 例(5.1%)患者为产后起病。根据临床、实验室和肝活检结果,其中 2 例患者被认为存在亚临床 AIH,产后因疾病发作而确诊。另 1 例则被认为是产后新发病例。

结论

AIH 可在产后起病,如果产后出现肝功能障碍,应积极考虑该病的鉴别诊断。

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