Researcher, National Collaborating Centre for Cancer, Cardiff, United Kingdom.
J Thorac Oncol. 2012 May;7(5):821-4. doi: 10.1097/JTO.0b013e31824afc55.
In the U.K. more than 40,000 people are diagnosed with lung cancer every year and an estimated 65,000 people are living with lung cancer. The most effective follow-up strategy for these patients is undetermined. This article reports a systematic review of studies comparing different follow-up strategies for patients with lung cancer.
We searched Medline, Premedline, Embase, Cochrane Library, Cinahl, BNI, Psychinfo, Amed, Web of Science (SCI & SSCI), and Biomed Central and included any original study published in English comparing one type of follow-up strategy to another in patients with lung cancer who had received treatment with curative or palliative intent and/or best supportive care. Studies were included if there were 50 patients or more per follow-up group.
Of the four included studies that compared different follow-up strategies in patients with lung cancer, one was a randomized controlled trial and three were retrospective. The studies all examined different follow-up strategies and tended to be marked by various limitations. No formal data synthesis was therefore possible. However, in one article there was some evidence that regular review was associated with less emergency-department crisis attendances than symptom-generated review.
The included studies were marked by a number of methodological compromises. On the basis of the reported body of evidence it is therefore not possible to make any firm conclusions about the most effective follow-up strategy but the review has identified a need for urgent research into all aspects of follow-up.
在英国，每年有超过 40000 人被诊断出患有肺癌，约有 65000 人患有肺癌。这些患者最有效的随访策略尚未确定。本文报告了一项系统评价，比较了不同的随访策略在治疗和姑息治疗以及/或最佳支持治疗后的肺癌患者中的效果。
我们检索了 Medline、Premedline、Embase、Cochrane Library、Cinahl、BNI、Psychinfo、Amed、Web of Science（SCI 和 SSCI）和 Biomed Central，并纳入了所有以英语发表的比较不同随访策略的原始研究，这些研究的对象是接受过治愈性或姑息性治疗和/或最佳支持治疗的肺癌患者，且每组随访患者至少有 50 例。
四项纳入的研究比较了不同的肺癌患者随访策略，其中一项为随机对照试验，三项为回顾性研究。这些研究都检查了不同的随访策略，并且往往存在各种局限性。因此，无法进行正式的数据综合。然而，有一篇文章有一些证据表明，定期检查与因症状而进行的检查相比，急诊就诊的危机事件更少。
纳入的研究存在许多方法学上的缺陷。因此，根据报告的证据，无法对最有效的随访策略做出任何明确的结论，但该综述确实需要对随访的各个方面进行紧急研究。
