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使用锥形束计算机断层扫描(CBCT)对多孔羟基磷灰石和氧化铝陶瓷眼眶植入物进行评估:一种用于体内多孔结构评估和监测的方法。

Porous Hydroxyapatite and Aluminium-Oxide Ceramic Orbital Implant Evaluation Using CBCT Scanning: A Method for In Vivo Porous Structure Evaluation and Monitoring.

作者信息

Lukáts Olga, Bujtár Péter, Sándor George K, Barabás József

机构信息

Department of Ophthalmology, Semmelweis University, Budapest 1083, Hungary.

出版信息

Int J Biomater. 2012;2012:764749. doi: 10.1155/2012/764749. Epub 2012 Feb 28.

Abstract

Objective. This study aimed to define CBCT as a technique for postimplantation in vivo examination of porous hydroxyapatite and aluminium-oxide orbital implant shape, volume and density changes. Methods and Materials. CBCT was used to evaluate 30 enucleated patients treated with spherical polyglactin 910 wrapped hydroxyapatite and aluminum-oxide orbital implants. The mean duration of patient followup was 3.2 years or 1338 days with a range of 0.2 to 7.2 years or 79 to 2636 days in a population with an average age of 40.8 years. Results. The resolution of currently clinically used CBCT equipment allowed detailed structural observation of the orbital hydroxyapatite implants with some modifications. Volume and shape estimations were possible while density evaluation was more complicated compared to medical source computed tomography. The mean densities of the orbital implants were followed and a consistent gradual decrease identified from the beginning of implantation which was better defined after the applied correction procedure. Conclusion. CBCT with lower dosages of radiation exposure can be used to follow changes in implanted high-density porous structures. The density evaluation is possible with calibration modifications. Changes in orbital implant densities identified in this study may correspond to healing and maturation of soft tissues surrounding and penetrating the implants.

摘要

目的。本研究旨在将锥形束计算机断层扫描(CBCT)定义为一种用于在体内检查多孔羟基磷灰石和氧化铝眼眶植入物植入后形状、体积和密度变化的技术。方法和材料。使用CBCT对30例接受球形聚乙醇酸910包裹的羟基磷灰石和氧化铝眼眶植入物治疗的眼球摘除患者进行评估。患者的平均随访时间为3.2年或1338天,年龄平均为40.8岁的人群中,随访时间范围为0.2至7.2年或79至2636天。结果。目前临床使用的CBCT设备的分辨率允许对眼眶羟基磷灰石植入物进行详细的结构观察,但需进行一些改进。体积和形状估计是可行的,而与医用源计算机断层扫描相比,密度评估更为复杂。对眼眶植入物的平均密度进行了跟踪,并确定从植入开始密度持续逐渐降低,在应用校正程序后更清晰。结论。低辐射剂量的CBCT可用于跟踪植入的高密度多孔结构的变化。通过校准修改可以进行密度评估。本研究中确定的眼眶植入物密度变化可能与植入物周围和穿透植入物的软组织的愈合和成熟有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9538/3299339/ced064bae47e/IJBM2012-764749.001.jpg

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