Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Am J Med. 2012 May;125(5):485-90. doi: 10.1016/j.amjmed.2011.11.025.
The effect of exercise on sleep-disordered breathing is unknown. While diet and weight loss have been shown to reduce the severity of sleep-disordered breathing, it is unclear whether exercise has an independent effect.
A population-based longitudinal epidemiologic study of adults measured the association between exercise and incidence and severity of sleep-disordered breathing. Hours of weekly exercise were assessed by 2 mailed surveys (1988 and 2000). Sleep-disordered breathing was assessed by 18-channel in-laboratory polysomnography at baseline and at follow-up.
Associations were modeled using linear and logistic regression, adjusting for body mass index, age, sex, and other covariates. Hours of exercise were associated with reduced incidence of mild (odds ratio 0.76, P=.011) and moderate (odds ratio 0.67, P=.002) sleep-disordered breathing. A decrease in exercise duration also was associated with worsening sleep-disordered breathing, as measured by the apnea-hypopnea index (β=2.368, P=.048). Adjustment for body mass index attenuated these effects.
Exercise is associated with a reduced incidence of mild and moderate sleep-disordered breathing, and decreasing exercise is associated with worsening of sleep-disordered breathing. The effect of exercise on sleep-disordered breathing appears to be largely, but perhaps not entirely, mediated by changes in body habitus.
运动对睡眠呼吸紊乱的影响尚不清楚。虽然饮食和减肥已被证明可以减轻睡眠呼吸紊乱的严重程度，但运动是否有独立的影响尚不清楚。
一项基于人群的成年人纵向流行病学研究，测量了运动与睡眠呼吸紊乱的发生率和严重程度之间的关系。每周运动时间通过 2 次邮寄调查（1988 年和 2000 年）进行评估。睡眠呼吸紊乱通过基线和随访时的 18 通道实验室多导睡眠图进行评估。
使用线性和逻辑回归模型对关联进行建模，调整了体重指数、年龄、性别和其他协变量。运动时间与轻度（比值比 0.76，P=.011）和中度（比值比 0.67，P=.002）睡眠呼吸紊乱的发生率降低相关。运动持续时间的减少也与睡眠呼吸紊乱的恶化相关，这是通过呼吸暂停低通气指数（β=2.368，P=.048）来衡量的。调整体重指数后，这些影响减弱了。
运动与轻度和中度睡眠呼吸紊乱的发生率降低有关，而运动减少与睡眠呼吸紊乱的恶化有关。运动对睡眠呼吸紊乱的影响似乎主要（但并非完全）是通过身体形态的变化来介导的。
