UC San Diego Department of Medicine, 9500 Gilman Drive, UC San Diego, La Jolla, CA, 92037, USA.
Curr Diab Rep. 2023 Jul;23(7):165-171. doi: 10.1007/s11892-023-01510-6. Epub 2023 May 6.
To synthesize the existing literature regarding the complex interplay between sleep disturbance, obesity, and diabetes. The review emphasizes the three pillars of health being diet, exercise, and sleep, with the notion that if one is ignored, then the other two could suffer.
Sleep deprivation is associated with incident obesity, perhaps mediated by dysregulation in leptin and ghrelin - hormones important in regulation of appetite. Sleep apnea is very common particularly among obese people with type 2 diabetes mellitus. Treatment of sleep apnea has clear symptomatic benefits although its impact on long-term cardiometabolic health is less clear. Sleep disturbance may be an important modifiable risk for patients at risk of cardiometabolic disease. An assessment of sleep health may be an important component of the comprehensive care of patients with obesity and diabetes mellitus.
综合现有关于睡眠障碍、肥胖和糖尿病之间复杂相互作用的文献。本综述强调了健康的三个支柱：饮食、运动和睡眠，即如果忽视其中一个，其他两个可能会受到影响。
睡眠不足与肥胖的发生有关，这可能是通过调节瘦素和胃饥饿素的紊乱介导的，瘦素和胃饥饿素在调节食欲方面非常重要。睡眠呼吸暂停在 2 型糖尿病肥胖患者中非常常见。尽管治疗睡眠呼吸暂停症对长期心脏代谢健康的影响尚不清楚，但它具有明显的症状益处。睡眠障碍可能是发生心脏代谢疾病风险患者的一个重要可改变的危险因素。评估睡眠健康可能是肥胖和糖尿病患者综合治疗的一个重要组成部分。
