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睡眠呼吸障碍的差异:上游风险因素、机制和影响。

Disparities in Sleep-Disordered Breathing: Upstream Risk Factors, Mechanisms, and Implications.

机构信息

Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.

Children's Hospital of Philadelphia, 2716 South Street Boulevard, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Clin Chest Med. 2023 Sep;44(3):585-603. doi: 10.1016/j.ccm.2023.03.012. Epub 2023 May 8.

Abstract

Sleep-disordered breathing (SDB) refers to a spectrum of disorders ranging from habitual snoring without frank episodes of obstructed breathing or desaturation during sleep to obstructive sleep apnea, where apneas and hypopneas repetitively occur with resultant intermittent hypoxia, arousal, and sleep disruption. Disparities in SDB reflect its overall high prevalence in children and adults from racially and ethnically minoritized or low socioeconomic status backgrounds coupled with high rates of underdiagnosis and suboptimal treatment.

摘要

睡眠呼吸障碍(SDB)是指一系列疾病,范围从习惯性打鼾到睡眠中无明显呼吸受阻或低氧血症,再到阻塞性睡眠呼吸暂停,其中呼吸暂停和低通气反复出现,导致间歇性低氧血症、觉醒和睡眠中断。SDB 的差异反映了其在种族和民族少数群体或社会经济地位较低的儿童和成人中的总体高患病率,以及诊断不足和治疗效果不佳的高发生率。

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