Department of Obstetrics and Gynecology, Institute of Clinical Sciences, University Hospital of Skane, Malmö, Sweden.
Am J Obstet Gynecol. 2012 Jun;206(6):476.e1-8. doi: 10.1016/j.ajog.2012.02.036. Epub 2012 Mar 7.
We sought to analyze the prevalence and clinical manifestations of Mycoplasma genitalium infection in a heterogeneous population of women.
The study was designed as a cross-sectional case-control study. Women attending a gynecological outpatient service from 2003 through 2008 were invited to participate.
The prevalence of M genitalium was 2.1% and of Chlamydia trachomatis was 2.8% among 5519 tested women. A total of 679 women were included. Both pelvic inflammatory disease (PID) and cervicitis were independently associated with M genitalium (odds ratio, 9.00; 95% confidence interval, 1.62-49.89 and odds ratio, 3.80; 95% confidence interval, 2.06-7.03, respectively). Women with C trachomatis had a higher frequency of both PID (18.3% vs 4.9%, P < .001) and cervicitis (33.4% vs 22.3%, P < .001) than women with M genitalium.
M genitalium was an independent and strong risk factor for both cervicitis and PID although, compared to C trachomatis, clinical manifestations were less frequent.
我们旨在分析支原体属（Mycoplasma）生殖器感染在不同人群女性中的流行率和临床表现。
本研究设计为横断面病例对照研究。2003 年至 2008 年期间，邀请在妇科门诊就诊的女性参与研究。
在接受检测的 5519 名女性中，支原体属（Mycoplasma）生殖器感染的流行率为 2.1%，沙眼衣原体（Chlamydia trachomatis）的流行率为 2.8%。共纳入 679 名女性。盆腔炎（PID）和宫颈炎均与支原体属（Mycoplasma）生殖器感染独立相关（比值比，9.00；95%置信区间，1.62-49.89 和比值比，3.80；95%置信区间，2.06-7.03）。感染沙眼衣原体（Chlamydia trachomatis）的女性中 PID（18.3% vs 4.9%，P <.001）和宫颈炎（33.4% vs 22.3%，P <.001）的发生率均高于感染支原体属（Mycoplasma）生殖器感染的女性。
支原体属（Mycoplasma）生殖器感染是宫颈炎和 PID 的独立且强烈的危险因素，尽管与沙眼衣原体（Chlamydia trachomatis）相比，临床表现较少见。
