Spoor T C, Hartel W C, Lensink D B, Wilkinson M J
Kresge Eye Institute, Wayne State University, Detroit, MI 48201.
Am J Ophthalmol. 1990 Dec 15;110(6):665-9. doi: 10.1016/s0002-9394(14)77065-5.
We treated 21 patients (22 eyes) with traumatic optic neuropathy by using intravenous megadose methylprednisolone (13 patients) or high-dose dexamethasone (eight patients). Of 13 patients treated with megadose methylprednisolone, 12 had improved visual function, as did seven of nine eyes treated with intravenous dexamethasone. This difference was not significant (P = .3). Initial total blindness, mechanism of injury, or time from injury to treatment did not correlate with visual improvement.
我们对21例（22只眼）外伤性视神经病变患者采用静脉注射大剂量甲基强的松龙（13例）或大剂量地塞米松（8例）进行治疗。在接受大剂量甲基强的松龙治疗的13例患者中，12例视觉功能有所改善；在接受静脉注射地塞米松治疗的9只眼中，有7只眼视觉功能改善。这种差异无统计学意义（P = 0.3）。初始完全失明、损伤机制或受伤至治疗的时间与视力改善无关。
