Fundación Instituto Valenciano de Oncología (IVO), Valencia, Spain. jguinot@fi vo.org
Clin Transl Oncol. 2012 Apr;14(4):263-70. doi: 10.1007/s12094-012-0794-2.
Radiotherapy (RT) is commonly used as adjuvant treatment following hysterectomy and double oophorectomy in endometrial carcinoma. Prophylactic vaginal brachytherapy (BT) is the most common treatment in BT units. The PORTEC and GOG 99 studies have attempted to clarify the indications of BT and postoperative external RT, changing treatment standards. However, prophylactic BT regimens are very varied and there is currently no consensus on how to treat patients in terms of dose per fraction and number of fractions. Moreover, unoperated cases of endometrium are uncommon and there is limited experience in their treatment with BT. The 9th Consensus Meeting of the SEOR and SEFM Brachytherapy Group, held in Malaga on 11 March 2011, was therefore dedicated to "Brachytherapy in Endometrial Carcinoma". This article presents the consensus on treatment of endometrial carcinoma in operated (prophylactic vaginal BT) and unoperated (endouterine BT) patients.
放疗(RT)常用于子宫内膜癌子宫切除和双侧卵巢切除术后的辅助治疗。预防性阴道近距离放疗(BT)是 BT 单位中最常见的治疗方法。PORTEC 和 GOG 99 研究试图阐明 BT 和术后外照射 RT 的适应证,改变了治疗标准。然而,预防性 BT 方案差异很大,目前对于如何根据分次剂量和分次次数来治疗患者尚无共识。此外,未手术的子宫内膜病例并不常见,用 BT 治疗的经验有限。因此,2011 年 3 月 11 日在马拉加举行的 SEOR 和 SEFM 近距离治疗小组第 9 次共识会议专门讨论了“子宫内膜癌的近距离治疗”。本文介绍了手术(预防性阴道 BT)和未手术(经阴道 BT)患者子宫内膜癌治疗的共识。