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以血清钙为标志物的绝经前后女性的牙槽骨量:一项对比研究。

Alveolar bone mass in pre- and postmenopausal women with serum calcium as a marker: a comparative study.

作者信息

Ramesh Amitha, Mahajan Karishma, Thomas Biju, Shenoy Nina, Bhandary Rahul

机构信息

Department of Periodontics, AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India.

出版信息

Indian J Dent Res. 2011 Nov-Dec;22(6):878. doi: 10.4103/0970-9290.94667.

DOI:10.4103/0970-9290.94667
PMID:22484895
Abstract

CONTEXT

In most women bone mass reaches its peak in the third decade of life and declines thereafter with the onset of menopause and might lead to osteoporosis. Osteoporosis may result in reduced jaw bone mass and alterations of the mandibular structure. Qualitative and quantitative indices have been used for panoramic radiographs to assess the alveolar bone quality.

AIMS

The purpose of this study was to compare the alveolar bone quality of premenopausal and postmenopausal women using the panoramic mandibular index (PMI). This study also aimed to estimate the levels of serum calcium in premenopausal and postmenopausal women.

SETTINGS AND DESIGN

Single centre case control study.

MATERIALS AND METHODS

A total of 30 patients were divided into three groups of ten each - the healthy group, control group, and study group. Alveolar bone mass was evaluated by the PMI. Serum calcium was also assessed for all the patients.

STATISTICAL ANALYSIS USED

The results obtained were subjected to statistical analysis by one-way analysis of variance using Statistical Software SPSS version 17, Tukey test for comparision, Pearson's correlation coefficient was employed.

RESULTS

Premenopausal women had the highest values for alveolar cortical bone mass as recorded by the PMI, followed by postmenopausal women with a healthy periodontium. The lowest values were recorded in the group of postmenopausal women with chronic generalized periodontitis. Similar results were found for serum calcium values.

CONCLUSION

Postmenopausal women exhibit a reduced alveolar bone mass and lowered levels of serum total calcium with the increasing age. These changes may be useful indicators for low skeletal bone mineral density or osteoporosis.

摘要

背景

在大多数女性中,骨量在生命的第三个十年达到峰值,此后随着更年期的开始而下降,并可能导致骨质疏松症。骨质疏松症可能导致颌骨骨量减少和下颌结构改变。定性和定量指标已用于全景X线片以评估牙槽骨质量。

目的

本研究的目的是使用全景下颌指数(PMI)比较绝经前和绝经后女性的牙槽骨质量。本研究还旨在估计绝经前和绝经后女性的血清钙水平。

设置与设计

单中心病例对照研究。

材料与方法

总共30名患者分为三组,每组10人——健康组、对照组和研究组。通过PMI评估牙槽骨量。还对所有患者进行了血清钙评估。

所用统计分析方法

使用统计软件SPSS 17版通过单因素方差分析对所得结果进行统计分析,采用Tukey检验进行比较,采用Pearson相关系数。

结果

PMI记录显示,绝经前女性的牙槽皮质骨量最高,其次是牙周健康的绝经后女性。绝经后患有慢性广泛性牙周炎的女性组记录的数值最低。血清钙值也得到了类似结果。

结论

随着年龄的增长,绝经后女性的牙槽骨量减少,血清总钙水平降低。这些变化可能是低骨矿物质密度或骨质疏松症的有用指标。

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