Chandak Lina Govind, Lohe Vidya Krushnarao, Bhowate Rahul R, Gandhi Krushna P, Vyas Neha V
Department of Oral Medicine and Radiology, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences (Deemed University) Sawangi, Wardha, Maharashtra, India.
Contemp Clin Dent. 2017 Jan-Mar;8(1):53-58. doi: 10.4103/0976-237X.205044.
Osteoporosis is a disease that is seen commonly with increasing age. The purpose of this study was to compare the bone quality of pre- and post-menopausal women using the quantitative indices determined by measurements on panoramic radiographs (mental index, inferior and superior panoramic mandibular indices, antegonion index [AGI], and gonion index) and to determine the effects of serum calcium and serum estradiol levels on alveolar bone loss.
Sixty female patients in the age group of 25-55 years were included in the study. The patients were divided into three equal groups, i.e., control Group A (twenty - premenopausal women), study Group B (twenty - postmenopausal women with healthy periodontium), study Group C (twenty - postmenopausal women with periodontitis). Quantitative indices were measured on digital panoramic radiographs of the patients and serum calcium and estradiol levels were determined.
Correlation of serum calcium with radiomorphometric indices of all the groups showed statistically nonsignificant differences. On correlating mean estradiol levels with radiographic indices of patients of Group A and Group B showed statistically nonsignificant differences. On correlating mean estradiol levels with radiographic indices of patients of Group C patients showed statistically significant difference with positive correlation with cortical width ( = 0.04) and AGI ( = 0.02) while statistically nonsignificant correlation with other indices. The statistical tests used for the analysis of the result were one-way ANOVA, multiple comparison Tukey test, Chi-square test, Student's -test.
There is a little evidence of correlation of these indices with serum estradiol and calcium levels, and therefore, detailed further research about this correlation is required.
骨质疏松症是一种随着年龄增长而常见的疾病。本研究的目的是使用全景X线片测量所确定的定量指标（颏孔指数、全景下颌上下指数、下颌角前切迹指数[AGI]和下颌角指数）比较绝经前和绝经后女性的骨质量，并确定血清钙和血清雌二醇水平对牙槽骨吸收的影响。
本研究纳入了60名年龄在25 - 55岁的女性患者。患者被分为三组，每组20人，即对照组A（20名绝经前女性）、研究组B（20名牙周健康的绝经后女性）、研究组C（20名患有牙周炎的绝经后女性）。对患者的数字化全景X线片测量定量指标，并测定血清钙和雌二醇水平。
所有组血清钙与放射形态计量学指标的相关性显示无统计学显著差异。将A组和B组患者的平均雌二醇水平与放射学指标进行相关性分析，显示无统计学显著差异。将C组患者的平均雌二醇水平与放射学指标进行相关性分析，显示与皮质骨宽度（P = 0.04）和AGI（P = 0.02）呈正相关有统计学显著差异，而与其他指标的相关性无统计学意义。用于分析结果的统计检验包括单因素方差分析、多重比较Tukey检验、卡方检验、Student's t检验。
这些指标与血清雌二醇和钙水平相关性的证据很少，因此，需要对此相关性进行更详细的进一步研究。
