Nayak Chaturbhuja, Singh Vikram, Singh V P, Oberai Praveen, Roja Varanasi, Shitanshu Shashi Shekhar, Sinha M N, Deewan Deepti, Lakhera B C, Ramteke Sunil, Kaushik Subhash, Sarkar Sarabjit, Mandal N R, Mohanan P G, Singh J R, Biswas Sabyasachi, Mathew Georgekutty
Central Council for Research in Homoeopathy, New Delhi, India.
Homeopathy. 2012 Apr;101(2):84-91. doi: 10.1016/j.homp.2012.02.002.
The primary objective was to ascertain the therapeutic usefulness of homeopathic medicine in the management of chronic sinusitis (CS).
Multicentre observational study at Institutes and Units of the Central Council for Research in Homoeopathy, India. Symptoms were assessed using the chronic sinusitis assessment score (CSAS). 17 pre-defined homeopathic medicines were shortlisted for prescription on the basis of repertorisation for the pathological symptoms of CS. Regimes and adjustment of regimes in the event of a change of symptoms were pre-defined. The follow-up period was for 6 months. Statistical analysis was done using SPSS version 16.
628 patients suffering from CS confirmed on X-ray were enrolled from eight Institutes and Units of the Central Council for Research in Homoeopathy. All 550 patients with at least one follow-up assessment were analyzed. There was a statistically significant reduction in CSAS (P = 0.0001, Friedman test) after 3 and 6 months of treatment. Radiological appearances also improved. A total of 13 out of 17 pre-defined medicines were prescribed in 550 patients, Sil. (55.2% of 210), Calc. (62.5% of 98), Lyc. (69% of 55), Phos. (66.7% of 45) and Kali iod. (65% of 40) were found to be most useful having marked improvement. 4/17 medicines were never prescribed. No complications were observed during treatment.
Homeopathic treatment may be effective for CS patients. Controlled trials are required for further validation.
主要目的是确定顺势疗法药物在慢性鼻窦炎（CS）管理中的治疗效用。
在印度顺势疗法中央研究理事会的各研究所和单位开展多中心观察性研究。使用慢性鼻窦炎评估评分（CSAS）对症状进行评估。根据针对CS病理症状的方剂学，筛选出17种预先定义的顺势疗法药物用于处方。预先定义了症状变化时的治疗方案及调整方案。随访期为6个月。使用SPSS 16版进行统计分析。
从印度顺势疗法中央研究理事会的8个研究所和单位招募了628例经X线确诊为CS的患者。对所有550例至少有一次随访评估的患者进行了分析。治疗3个月和6个月后，CSAS有统计学意义的降低（P = 0.0001，Friedman检验）。影像学表现也有所改善。550例患者中共使用了17种预先定义药物中的13种，发现Sil.（210例中的55.2%）、Calc.（98例中的62.5%）、Lyc.（55例中的69%）、Phos.（45例中的66.7%）和Kali iod.（40例中的65%）最为有效，有明显改善。17种药物中有4种从未被处方。治疗期间未观察到并发症。
顺势疗法治疗可能对CS患者有效。需要进行对照试验以进一步验证。
