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腹腔镜直肠癌全直肠系膜切除术:病例系列

Laparoscopic TME for rectal cancer: a case series.

作者信息

Day Andrew, Smith Ralph, Jourdan Iain, Rockall Tim

机构信息

Minimal Access Therapy Training Unit, Postgraduate Medical School, University of Surrey, Guildford, UK.

出版信息

Surg Laparosc Endosc Percutan Tech. 2012 Apr;22(2):e98-101. doi: 10.1097/SLE.0b013e318245d574.

Abstract

PURPOSE

Laparoscopic colonic resection for cancer is becoming well established within the surgical community. However, the current evidence for laparoscopic total mesorectal excision (TME) is scanty but does point toward a potential for improved short-term outcomes and oncological equivalency to open resection.

METHODS

Patients undergoing laparoscopic TME for rectal cancer in 1 hospital between October 2003 and December 2010 were analyzed. Data were collated from a prospective database. Survival analysis was calculated using the Kaplan-Meier method.

RESULTS

79 patients were analyzed (96.3% of all TMEs). There was a median length of stay of 5 days, with no postoperative mortality. The 5-year overall survival was 70% and the 5-year disease-free survival was 65.5%. There was a conversion rate of 10.1%. The 5-year overall survival for completed laparoscopic cases was 70.6% versus 62.5% for converted cases (P=0.041).

CONCLUSIONS

There seems to be increasing evidence that laparoscopic TME is equivalent to open TME for rectal cancer. Conversion may be deleterious to overall survival.

摘要

目的

腹腔镜结肠癌切除术在外科领域正逐渐得到广泛认可。然而,目前关于腹腔镜全直肠系膜切除术(TME)的证据较少,但确实表明其有可能改善短期预后并在肿瘤学方面与开放手术相当。

方法

对2003年10月至2010年12月期间在1家医院接受腹腔镜TME治疗直肠癌的患者进行分析。数据来自前瞻性数据库。采用Kaplan-Meier方法进行生存分析。

结果

共分析了79例患者(占所有TME手术的96.3%)。中位住院时间为5天,无术后死亡病例。5年总生存率为70%,5年无病生存率为65.5%。中转率为10.1%。完成腹腔镜手术病例的5年总生存率为70.6%,中转病例为62.5%(P = 0.041)。

结论

越来越多的证据表明,腹腔镜TME治疗直肠癌与开放TME相当。中转手术可能对总生存率有害。

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