Department of Radiation Oncology, H. Lee Moffitt Cancer Center & Research Institute Tampa, FL 33612, USA.
Cancer Control. 2012 Apr;19(2):84-91. doi: 10.1177/107327481201900202.
Bone metastases occur frequently in patients with advanced cancer and are a serious complication of cancer. The decision to treat is often individualized, based on each patient's clinical presentation, life expectancy, and quality of life.
We reviewed the current literature pertaining to management of metastatic disease to bone, and the medical, radiotherapeutic, and surgical treatment options for management of bone metastasis are discussed.
Current management of skeletal metastasis includes analgesia, systemic therapy, radiation therapy, and surgery. We propose treatment algorithms for management of vertebral and nonvertebral bone metastases and suggest individualized interventions based on clinical presentation.
Management of bone metastases is complex and requires a multidisciplinary approach. The goal of treatment is often palliative, and intervention and treatment regimens should be individualized based on the specific clinical presentation of each patient.
晚期癌症患者常发生骨转移，这是癌症的严重并发症。治疗决策通常是个体化的，基于每个患者的临床表现、预期寿命和生活质量。
我们回顾了目前关于骨转移管理的文献，并讨论了治疗骨转移的医学、放射治疗和手术治疗选择。
目前骨骼转移的管理包括镇痛、全身治疗、放射治疗和手术。我们提出了治疗椎体和非椎体骨转移的治疗算法，并根据临床表现提出了个体化干预措施。
骨转移的管理是复杂的，需要多学科的方法。治疗的目的通常是姑息性的，干预和治疗方案应根据每个患者的具体临床表现个体化。
