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转移性脊柱肿瘤的外科治疗。

Surgical management of metastatic spinal tumors.

机构信息

Department of Neurological Surgery, Johns Hopkins Hospital, Johns Hopkins University, Baltimore, MD 21287, USA.

出版信息

Cancer Control. 2012 Apr;19(2):122-8. doi: 10.1177/107327481201900206.

Abstract

BACKGROUND

The spine is the most common site of skeletal metastases. The evolution of surgical methods, medical treatment, and radiation therapy has led to improved survival, functional status, and quality of life for patients with cancer. The role of surgery in the treatment of patients with spinal metastases has evolved over time.

METHODS

A review of publications describing the role of open surgery and vertebroplasty was performed and the results are summarized.

RESULTS

The treatment goals of spinal metastases include the preservation and restoration of neurologic function and spinal stability. Modern imaging modalities provide accurate methods of tumor diagnosis. A variety of approaches and stabilization techniques are available and should be tailored to the location of the tumor and systemic comorbidities.

CONCLUSIONS

As part of multidisciplinary treatment that includes radiation therapy and chemotherapy, surgery provides an effective method of restoration and preservation of neurologic function and spinal stability for patients with metastatic spinal tumors.

摘要

背景

脊柱是骨骼转移最常见的部位。随着手术方法、医学治疗和放射治疗的发展,癌症患者的生存率、功能状态和生活质量得到了提高。手术在治疗脊柱转移患者中的作用也随着时间的推移而发展。

方法

对描述开放手术和椎体成形术作用的文献进行了回顾,并对结果进行了总结。

结果

脊柱转移的治疗目标包括保留和恢复神经功能和脊柱稳定性。现代影像学方法提供了肿瘤诊断的准确方法。有多种方法和稳定技术可供选择,应根据肿瘤的位置和全身合并症进行定制。

结论

作为包括放射治疗和化学治疗在内的多学科治疗的一部分,手术为患有转移性脊柱肿瘤的患者提供了一种有效恢复和保留神经功能和脊柱稳定性的方法。

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