Mesfin Addisu, Buchowski Jacob M, Gokaslan Ziya L, Bird Justin E
J Am Acad Orthop Surg. 2015 Jan;23(1):38-46. doi: 10.5435/JAAOS-23-01-38.
The skeletal system is the third most common site of metastases after the lung and liver. Within the skeletal system, the vertebral column is the most common site of metastases, and 8% to 15% of vertebral metastases are in the cervical spine, consisting, anatomically and biomechanically, of the occipitocervical junction, subaxial spine, and cervicothoracic junction. The vertebral body is more commonly affected than the posterior elements. Nonsurgical management techniques include radiation therapy (stereotactic and conventional), bracing, and chemotherapy. Surgical techniques include percutaneous methods, such as vertebroplasty, and palliative methods, such as decompression and stabilization. Surgical approach depends on the location of the tumor and the goals of the surgery. Appropriate patient selection can lead to successful surgical outcomes by restoring spinal stability and improving quality of life.
骨骼系统是继肺和肝之后转移瘤的第三大常见部位。在骨骼系统中，脊柱是转移瘤最常见的部位，8%至15%的脊柱转移瘤位于颈椎，从解剖学和生物力学角度来看，颈椎由枕颈交界区、下颈椎和颈胸交界区组成。椎体比后部结构更常受累。非手术治疗技术包括放射治疗（立体定向和传统放疗）、支具治疗和化疗。手术技术包括经皮方法，如椎体成形术，以及姑息性方法，如减压和稳定手术。手术入路取决于肿瘤的位置和手术目标。通过恢复脊柱稳定性和改善生活质量，恰当的患者选择可带来成功的手术结果。
