Ferenc C, Czeizel A, Lys F
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore.
Acta Paediatr Hung. 1990;30(2):169-89.
A number of published papers have dealt with the comparison of birth prevalences of congenital cardiovascular malformation (CCVMs). The feasibility of meaningful intercountry comparison was explored during the visiting fellowships to Dr Andrew Czeizel of Charlotte Ferencz and Dr Francine Lys. Data from three Hungarian studies, one USA and one Belgian study are presented here for selected CCVMs. Differential perinatal and diagnostic circumstances which lead to possible causes of bias involve four main domains: study population, ascertainment of cases, categorization of CCVMs and diagnostic definitions. Unique features are highlighted as a descriptive framework which will promote the comparability of epidemiologic data from various regions.
许多已发表的论文都涉及先天性心血管畸形（CCVMs）出生患病率的比较。夏洛特·费伦茨和弗朗辛·利斯博士在访问安德鲁·切泽尔博士期间探讨了进行有意义的国家间比较的可行性。本文展示了来自三项匈牙利研究、一项美国研究和一项比利时研究中选定CCVMs的数据。导致可能产生偏差原因的围产期和诊断情况差异涉及四个主要方面：研究人群、病例确定、CCVMs分类和诊断定义。突出独特特征作为一个描述性框架，这将促进不同地区流行病学数据的可比性。
