Department of Medicine, Palo Alto Medical Foundation, El Camino Hospital, Mountain View, California 94040, USA.
J Hosp Med. 2012 Apr;7 Suppl 4:S11-3. doi: 10.1002/jhm.1933.
Hyponatremia is relatively common in patients admitted with pneumonia, and it is associated with higher disease severity. The precise mechanism is incompletely understood, but the syndrome of inappropriate antidiuretic hormone secretion is felt to play a significant role. Traditional options to manage hyponatremia in such patients are fraught with challenges. The recently approved vasopressin receptor antagonists offer a new option for the management of this challenging condition.
低钠血症在肺炎住院患者中较为常见，且与疾病严重程度相关。其确切机制尚不完全清楚，但认为抗利尿激素分泌不当综合征起重要作用。传统的此类患者低钠血症治疗方法存在诸多挑战。最近批准的血管加压素受体拮抗剂为这种具有挑战性的疾病的治疗提供了新的选择。
