Hyponatremia in pneumonia.

Hyponatremia is relatively common in patients admitted with pneumonia, and it is associated with higher disease severity. The precise mechanism is incompletely understood, but the syndrome of inappropriate antidiuretic hormone secretion is felt to play a significant role. Traditional options to manage hyponatremia in such patients are fraught with challenges. The recently approved vasopressin receptor antagonists offer a new option for the management of this challenging condition.