Cupples Connie K, Cashion Ann K, Cowan Patricia A, Tutor Ruth S, Wicks Mona N, Williams Ruth, Eason James D
Union University, Germantown, Tennessee, USA.
Prog Transplant. 2012 Mar;22(1):62-70. doi: 10.7182/pit2012888.
Weight gain after kidney transplantation affects 50% to 90% of kidney transplant recipients. Factors leading to weight gain in recipients are thought to include a change in lifestyle (eg, dietary intake and physical activity), age, race, sex, and immunosuppressant medications.
To examine dietary intake and physical activity of kidney transplant recipients at baseline and 3 and 6 months after transplantation to identify contributing factors to weight gain.
Descriptive, correlational study using secondary data from a larger parent study examining genetic and environmental contributors to weight gain after kidney transplantation.
Forty-four kidney transplant recipients at a mid-South university hospital-based transplant institute who had dietary intake, physical activity, and clinical data at baseline and 3 and 6 months were included.
Dietary intake, physical activity, weight, and body mass index.
Mean weight gain increased by 6% from baseline to 6 months. Interestingly, dietary intake did not change significantly from baseline to 6 months. Hours of sleep per day decreased during the same period (P = .02). Dietary intake, physical activity, age, race, sex, and immunosuppression showed no significant relationship to weight gain at 6 months.
Little consideration has been given to dietary intake and physical activity of kidney transplant recipients and the effects of these variables on weight gain. Further studies with a larger sample are needed, as weight gain after transplantation is a significant risk factor for diminished long-term outcomes.
肾移植后体重增加影响50%至90%的肾移植受者。导致受者体重增加的因素被认为包括生活方式的改变（如饮食摄入和身体活动）、年龄、种族、性别和免疫抑制药物。
研究肾移植受者在基线时以及移植后3个月和6个月的饮食摄入和身体活动情况，以确定体重增加的促成因素。
描述性、相关性研究，使用来自一项更大的母研究的二次数据，该母研究考察肾移植后体重增加的遗传和环境因素。
纳入了美国中南部一家大学医院移植研究所的44名肾移植受者，他们在基线时以及3个月和6个月时均有饮食摄入、身体活动和临床数据。
饮食摄入、身体活动、体重和体重指数。
从基线到6个月，平均体重增加了6%。有趣的是，从基线到6个月，饮食摄入没有显著变化。同期每天的睡眠时间减少（P = 0.02）。饮食摄入、身体活动、年龄、种族、性别和免疫抑制在6个月时与体重增加均无显著关系。
肾移植受者的饮食摄入和身体活动以及这些变量对体重增加的影响很少受到关注。由于移植后体重增加是长期预后不良的一个重要危险因素，因此需要进行更大样本量的进一步研究。
