Cornelis G R
Unité de Microbiologie, Université catholique de Louvain-en-Woluwe.
Bull Mem Acad R Med Belg. 1990;145(6-7):280-7; discussion 287-8.
Pathogenic bacteria of the genus Yersinia (Y. enterocolitica, Y. pseudotuberculosis and Y. pestis) are pathogens of the invasive type. Although they provoke diseases as different as plague and enterocolitis, the molecular bases of their virulence appear to be surprisingly similar: a 70 kb plasmid confers a degree of resistance to the primary immune response and the presence or absence of chromosome encoded functions modulates virulence. The knowledge of the virulence functions that now emerges suggests the conversion of Y. enterocolitica as a life carrier.
耶尔森氏菌属的致病细菌(小肠结肠炎耶尔森氏菌、假结核耶尔森氏菌和鼠疫耶尔森氏菌)是侵袭性病原菌。尽管它们引发的疾病如鼠疫和小肠结肠炎各不相同,但其毒力的分子基础似乎惊人地相似:一个70 kb的质粒赋予了一定程度的对初次免疫反应的抗性,并且染色体编码功能的存在与否调节着毒力。目前所出现的关于毒力功能的知识表明小肠结肠炎耶尔森氏菌可作为一种带菌者。